Results 81 to 90 of about 3,904,331 (296)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Doctor Nurys Diéguez Andrés (1951-2016), mainstay of the Intensive Care Medicine in Las Tunas
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016 Doctor Nurys Nirma Diéguez Andrés is one of the outstanding personalities in the barely four decades of universal and free medicine in the Cuban province of Las Tunas. She started her graduate studies on Internal Medicine at Dr.
Orlando Rafael Serrano Barrera
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Making Medical History Relevant to Medical Students: The First Fifty Years of the Calgary History of Medicine Program and History of Medicine Days Conferences. [PDF]
J Hist Med Allied Sci, 2023 Stahnisch FW.
europepmc +1 more source
Recycling the evidence: different approaches to the reanalysis of gerontological data [PDF]
, 2005 In 1991 Professor Margot JEFFERYS and two colleagues interviewed "pioneers of geriatric medicine" of whom 60 were geriatricians. These data are now on disk and can be searched digitally. The interviews were long and focussed on the careers of the doctors
Bornat, Joanna
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
S&F_scienzaefilosofia.it, 2015 We will analyze a segment of the very complex theoretical background concerning the current History of Medicine. In this sense, it is indispensable to examine the social contextualization of medicine, its links to political and cultural history, i.e.
Amodio, Paolo
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History of evidence-based medicine
Indian Journal of Urology, 2011 This essay reviews the historical circumstances surrounding the introduction and evolution of evidence-based medicine. Criticisms of the approach are also considered.
Roger L Sur, Philipp Dahm
doaj +1 more source
History of medicine in medical education: new Italian pathways. [PDF]
J Med Libr Assoc, 2023 Iorio S, Gazzaniga V, Lippi D.
europepmc +1 more source
Prenatal Corticosteroids for Reducing Morbidity and mortality after Preterm Birth [PDF]
, 2005 Annotated and edited transcript of a Witness Seminar held on 15 June 2004. Introduction by Barbara Stocking, Oxfam. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2005.©The Trustee of the Wellcome Trust, London, 2005.All
REYNOLDS, LA, Tansey, EM
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