Results 41 to 50 of about 1,690,911 (305)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Frontiers in Ecology and Evolution, 2022 Two main hypotheses have been proposed to explain the contemporary distribution of Antarctic terrestrial biota. We assess whether the current distribution of maritime Antarctic populations of the freshwater copepod Boeckella poppei is the result of (1) a
Claudia S. Maturana +21 more
doaj +1 more source
GLHF: A Brief Overview of Gaming Cafes [PDF]
, 2017 My paper is on the history of internet and gaming cafes, focusing on how they are seen today, the problems they face and some potential solutions. Although my focus is on gaming cafes in America, because they are so popular overseas in Asian countries ...
Sun, John
core +1 more source
Spatial and temporal uplift history of South America from calibrated drainage analysis [PDF]
, 2017 A multidisciplinary approach is used to analyze the Cenozoic uplift history of South America.Residual depth anomalies of oceanic crust abutting this continent help to determine the pattern of present-day dynamic topography.
Hoggard, MJ +3 more
core +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Scientific ReportsHumans have a long history of transporting and trading plants, contributing to the evolution of domesticated plants. Theobroma cacao originated in the Neotropics from South America.
Claire Lanaud +22 more
doaj +1 more source
Emerging Infectious Diseases, 2011 Venezuelan equine encephalomyelitis (VEE) epizoodemics were reported at 6–10-year intervals in northern South America beginning in the 1920s. In 1937, epizootic VEE virus was isolated from infected horse brain and shown as distinct from the North ...
Karl M. Johnson +4 more
doaj +1 more source
Phylogeography and population genetics of the endemic Malagasy bat, Macronycteris commersoni s.s. (Chiroptera: Hipposideridae) [PDF]
PeerJ, 2019 Macronycteris commersoni (Hipposideridae), a bat species endemic to Madagascar, is widespread across the island and utilizes a range of habitat types including open woodland, degraded habitats, and forested areas from sea level to 1,325 m.
Andrinajoro R. Rakotoarivelo +3 more
doaj +2 more sources
History of inclusive physical education in South America
, 2019 We examined how the origins of education and special education have influenced inclusion in schools and in physical education (PE) in the South American region. National and constitutional legislation in every country in the region has followed international recommendations (e.g., the many campaigns and directives from the United Nations and others ...
Mauerberg-deCastro, Eliane +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source