Results 41 to 50 of about 2,119,795 (310)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Turbulent Sixties at Rutgers: An Interview with Richard P. McCormick
, 1997 Richard P. McCormick’s professional life has been so intertwined with Rutgers University’s history that it is difficult to imagine anyone who knows more about Rutgers or who has put a greater imprint on the institution.
Birkner, Michael J.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Para uma definição de Didática da História Towards a history didactics definition
Revista Brasileira de História, 2008 Este artigo visa definir a Didática da História de acordo com a atual bibliografia alemã, que a considera mais próxima da História do que da Educação. Associada à palavra Geschichtsdidaktik, essa definição se opõe aos conceitos de Didática da História ...
Oldimar Cardoso
doaj +1 more source
Report on a Boston University Conference December 7-8, 2012 on 'How Can the History and Philosophy of Science Contribute to Contemporary U.S. Science Teaching?' [PDF]
, 2014 This is an editorial report on the outcomes of an international conference sponsored by a grant from the National Science Foundation (NSF) (REESE-1205273) to the School of Education at Boston University and the Center for Philosophy and History of ...
Benétreau-Dupin, Yann, Garik, Peter
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Educating in History: Thinking Historically through Historical Reenactment
Social Sciences, 2022 This paper aimed to identify trends in the scientific literature that relate the link between two concepts: historical thinking and historical reenactment. The definition of both concepts and their commonalities were examined.
José-Manuel González-González +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Hungarian National Minority in Slovenia: Assessment of Protection and Integration after EU Accession [PDF]
Romanian Journal of European Affairs, 2013 The following paper will focus on the issue of the Hungarian minority protection in Slovenia. The first section introduces the Hungarian national minority, its main features and historical evolution.
Sigrid Lipott
doaj
Digital games based learning for history – problem solving or problematic?
Education in the North, 2021 This study follows the design and development of an educational digital game, Tales of Iona, which was designed to be used to promote understanding of the ancient Scottish island of Iona in upper primary or early secondary schools.
Katrina Foy
doaj +1 more source