Results 41 to 50 of about 2,271,562 (311)

Bott periodicity in the Hit Problem

open access: yes, 2014
In this short note, we use Robert Bruner's $\mathcal{A}(1)$-resolution of $P = \mathbb{F}_2[t]$ to shed light on the Hit Problem. In particular, the reduced syzygies $P_n$ of $P$ occur as direct summands of $\widetilde{P}^{\otimes n}$, where $\widetilde ...
Ault, Shaun V.
core   +1 more source

A perspective on the discovery of enzyme activators

open access: yesSLAS Discovery, 2022
Enzyme activation remains a largely under-represented and poorly exploited area of drug discovery despite some key literature examples of the successful application of enzyme activators by various mechanisms and their importance in a wide range of ...
Antonia Turberville   +4 more
doaj   +1 more source

Theory progress and applications of dielectric elastomers

open access: yesInternational Journal of Smart and Nano Materials, 2013
This paper summarizes the research progress of dielectric elastomer (DE) and its composite materials, including the introduction of materials, theoretical research development, and typical applications.
Liwu Liu, Yanju Liu, Jinsong Leng
doaj   +1 more source

Design and motion analysis of a frog-like jumping robot based on a soft body detonation drive

open access: yesMaterials & Design, 2023
Inspired by the instantaneous power of the hindlimbs of frogs and the dexterous posture adjustment of their forelimbs, a frog-like jumping robot based on a soft body detonation drive was designed. By combining the flexibility of silicone material and the
Yitao Pan   +5 more
doaj   +1 more source

LERC: Coordinated Cache Management for Data-Parallel Systems

open access: yes, 2017
Memory caches are being aggressively used in today's data-parallel frameworks such as Spark, Tez and Storm. By caching input and intermediate data in memory, compute tasks can witness speedup by orders of magnitude.
Letaief, Khaled B.   +3 more
core   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware   +13 more
wiley   +1 more source

Preliminary design and analysis of a cubic deployable support structure based on shape memory polymer composite

open access: yesInternational Journal of Smart and Nano Materials, 2016
The deployable structures based on shape memory polymer composites (SMPCs) have been developed for its unique properties, such as high reliability, low-cost, lightweight, and self-deployment without complex mechanical devices compared with traditional ...
Fengfeng Li   +6 more
doaj   +1 more source

AiZynthFinder: a fast, robust and flexible open-source software for retrosynthetic planning

open access: yesJournal of Cheminformatics, 2020
We present the open-source AiZynthFinder software that can be readily used in retrosynthetic planning. The algorithm is based on a Monte Carlo tree search that recursively breaks down a molecule to purchasable precursors.
Samuel Genheden   +5 more
doaj   +1 more source

Double hit and double expressors in lymphoma: Definition and treatment

open access: yesCancer, 2018
Emerging biologic subsets and new prognostic markers are significantly and adversely affecting curability after standard chemoimmunotherapy for aggressive B‐cell lymphomas.
P. Riedell, Sonali M. Smith
semanticscholar   +1 more source

A de novo molecular generation method using latent vector based generative adversarial network

open access: yesJournal of Cheminformatics, 2019
Deep learning methods applied to drug discovery have been used to generate novel structures. In this study, we propose a new deep learning architecture, LatentGAN, which combines an autoencoder and a generative adversarial neural network for de novo ...
Oleksii Prykhodko   +6 more
doaj   +1 more source

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