Results 41 to 50 of about 11,339 (266)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Analysis of the Influence of Selected Parameters on the Success Rate of Shotgun Firing on UAVs
In contemporary conflicts, land forces – including artillery units and even individual soldiers – have increasingly faced threats posed by small, inexpensive yet highly effective unmanned aerial systems (UAS).
Pemčák Ivan +5 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation. [PDF]
Radiation accidents frequently involve acute high dose partial body irradiation leading to victims with radiation sickness and cutaneous radiation syndrome that implements radiation-induced cell death.
Andreas Lamkowski +6 more
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Olive Pomace Oil as a Chainsaw Lubricant: First Results of Tests on Performance and Safety Aspects
The total loss lubrication system that is typical of chainsaws is responsible for a massive dispersion in the agro-forestry environment of highly impactful pollutants, mostly of fossil origin, often well known as carcinogenic substances, which, in ...
Roberto Fanigliulo +10 more
doaj +1 more source
Hydrophobic characteristics are widely used in the development of new materials, especially to be applied to the surface coating of materials. This involves amplification of the light exposure on the hydrophobic surface for energy-efficient buildings and
Sasongko, Mega Nur +7 more
core +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
In the period in which technical systems present themselves as protagonists of the space organization process, the activity of the lower circuit of the urban economy is presented as an important element to understand the relationship of the urban ...
Reynaldo Daivyd Lopes da Silva +1 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

