Results 41 to 50 of about 655,391 (262)
Scientific Reports, 2021 COVID-19 pandemic continues to obstruct social lives and the world economy other than questioning the healthcare capacity of many countries. Weather components recently came to notice as the northern hemisphere was hit by escalated incidence in winter ...
Naleen Chaminda Ganegoda +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Journal of Studies in Civil EngineeringWind comfort analyses and the evaluation of locations for efficient small-scale wind turbines rely heavily on the accurate prediction of turbulent wind fields in urban environments.
Mushfiq Al Arafa, Amira Zinat
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Results in EngineeringIndustrial emissions in developing regions pose catastrophic yet unquantified health-ecological threats, exemplified by Togo’s Kpémé phosphate plant. Current approaches fail to resolve atmospheric dispersion dynamics of toxic metal-laden TSP (e.g., Cd ...
Daouda Sama +7 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Analysis of the Influence of Selected Parameters on the Success Rate of Shotgun Firing on UAVs
Measurement Science ReviewIn contemporary conflicts, land forces – including artillery units and even individual soldiers – have increasingly faced threats posed by small, inexpensive yet highly effective unmanned aerial systems (UAS).
Pemčák Ivan +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Geophysical Research LettersOn 10 May 2024, Earth was hit by a CME that drove the largest geomagnetic storm in 20 years. Multi‐spacecraft observations previously showed that the ∼100 nT north‐south IMF bz variation was driven by Kelvin‐Helmholtz waves with wavelength ∼250 RE and ...
Katariina Nykyri +17 more
doaj +1 more source