Results 171 to 180 of about 30,382,849 (226)

Optimizing the Multimerization Properties of Quinoline-Based Allosteric HIV-1 Integrase Inhibitors. [PDF]

Viruses
Sun J, Kessl JJ.
europepmc   +1 more source

The HIV-1 Integrase: Modeling and Beyond [PDF]

, 2013
Rohit Arora, Luba Tchertanov
openaire   +1 more source

HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro. [PDF]

J Mol Biol
Li M, Yang R, Chen X, Wang H, Ghirlando R, Dimitriadis EK, Craigie R.   +6 more
europepmc   +1 more source

Effect of naturally occurring polymorphisms on HIV-1 integrase structure and dolutegravir binding in subtypes A1 and D

Ssekagiri A, Ssemwanga D, Bbosa N, Kateete DP, Jjingo D.   +4 more
europepmc   +1 more source

Design, synthesis and biological evaluation of indole-2-carboxylic acid derivatives as novel HIV-1 integrase strand transfer inhibitors. [PDF]

RSC Adv
Zhang RH, Chen GQ, Wang W, Wang YC, Zhang WL, Chen T, Xiong QQ, Zhao YL, Liao SG, Li YJ, Yan GY, Zhou M.   +11 more
europepmc   +1 more source

<i>N</i>-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants. [PDF]

ACS Infect Dis
Mahajan PS, Smith SJ, Li M, Craigie R, Hughes SH, Zhao XZ, Burke TR.   +6 more
europepmc   +1 more source

PIAS3 modulate HIV-1 integrase SUMOylation

Retrovirology, 2011
Saϊb Ali, Zamborlini Alessia, Magne Fabien, Paris Joris, Beauclair Guillaume   +4 more
doaj   +1 more source

Elucidating the Molecular Determinants of the Binding Modes of a Third-Generation HIV-1 Integrase Strand Transfer Inhibitor: The Importance of Side Chain and Solvent Reorganization. [PDF]

Viruses
Sun Q, Biswas A, Lyumkis D, Levy R, Deng N.   +4 more
europepmc   +1 more source

Discovery of HIV-1 Integrase Inhibitors

, 2014
openaire   +1 more source

Binding Aspects of Baicalein to HIV-1 Integrase

Molecules and Cells, 2001
Human immunodeficiency virus type 1 (HIV-1) integrase is an essential enzyme in the life cycle of the virus. It is responsible for catalyzing the insertion of the viral genome into the host cell chromosome. This integrase is an attractive target for the design of a HIV antiviral drug, because integrase has no human counterpart.
Bong-Jin Lee, Jong-Wan Kim, Sung-Yün Lee   +2 more
exaly   +3 more sources