Results 1 to 10 of about 318,673 (186)

Evaluation and diagnostic usefulness of saliva for detection of HIV antibodies: A cross-sectional study

open access: yesJournal of Family Medicine and Primary Care, 2020
Background: Use of saliva as a specimen for detection of antibodies to infectious agents has generated particular interest in AIDS research community since 1980s.
Puneeta Vohra   +6 more
doaj   +2 more sources

HIV antibodies for treatment of HIV infection. [PDF]

open access: yesImmunol Rev, 2017
SummaryThe bar is high to improve on current combination antiretroviral therapy (ART), now highly effective, safe, and simple. However, antibodies that bind the HIV envelope are able to uniquely target the virus as it seeks to enter new target cells, or as it is expressed from previously infected cells. Furthermore, the use of antibodies against HIV as
Margolis DM, Koup RA, Ferrari G.
europepmc   +4 more sources

Feeding Eggs from Hens Immunized with Specific KLH-Conjugated HIV Peptide Candidate Vaccines to Chicks Induces Specific Anti-HIV gp120 and gp41 Antibodies that Neutralize the Original HIV Antigens [PDF]

open access: yesVaccine Research, 2020
Introduction: Isolation of antibodies from the egg yolk of chickens is of particular interest as a source of specific antibodies for oral administration to prevent infections and use them as immunodiagnostic reagents.
Justiz Vaillant   +3 more
doaj   +1 more source

HIV-gp140-Specific Antibodies Generated From Indian Long-Term Non-Progressors Mediate Potent ADCC Activity and Effectively Lyse Reactivated HIV Reservoir

open access: yesFrontiers in Immunology, 2022
Strategies to reduce the human immunodeficiency virus (HIV) reservoir are urgently required. The antibody-dependent cellular cytotoxicity (ADCC)-mediating anti-HIV antibodies have shown an association with HIV control.
Jayshree R. Dhande   +2 more
doaj   +1 more source

Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition – A Nested Case-Control Study in HIV-1 Serodiscordant Couples

open access: yesFrontiers in Immunology, 2022
Enveloped viruses, including the Human Immunodeficiency Virus-1 (HIV), incorporate host proteins such as human leucocyte antigens (HLA) into their envelope.
Melinda S. Suchard   +23 more
doaj   +1 more source

Adaptive HIV-specific B cell-derived humoral immune defenses of the intestinal mucosa in children exposed to HIV via breast-feeding. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: We evaluated whether B cell-derived immune defenses of the gastro-intestinal tract are activated to produce HIV-specific antibodies in children continuously exposed to HIV via breast-feeding. METHODS: Couples of HIV-1-infected mothers (n = 14)
Sandrine Moussa   +6 more
doaj   +1 more source

Rapid Point-of-Care Tests Using Staphylococcal Protein A Can Detect Early IgM Responses in HIV-1 and Treponema pallidum Infections

open access: yesMicrobiology Spectrum, 2022
Serological assays detecting IgM antibodies in addition to IgG antibodies have a diagnostic advantage in finding early infections. Staphylococcal protein A (SpA), widely used as an antibody-detecting reagent in various immunoassays, is considered to have
Valentina A. Schmidt   +3 more
doaj   +1 more source

Post-Immune Antibodies in HIV-1 Infection in the Context of Vaccine Development: A Variety of Biological Functions and Catalytic Activities

open access: yesVaccines, 2022
Unlike many other viruses, HIV-1 is highly variable. The structure of the viral envelope changes as the infection progresses and is one of the biggest obstacles in developing an HIV-1 vaccine.
Anna Timofeeva   +2 more
doaj   +1 more source

Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission

open access: yesFrontiers in Immunology, 2022
IntroductionInfants acquire maternal antibodies by Fc receptor transcytosis across the placenta during pregnancy. Fc receptors are expressed on immune cells and are important for activation of effector cell functions.MethodsIn this study, we evaluated Fc
Brittani M. Barrows   +47 more
doaj   +1 more source

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