Results 1 to 10 of about 2,450,636 (325)

HIV antibodies for treatment of HIV infection. [PDF]

Immunol Rev, 2017
SummaryThe bar is high to improve on current combination antiretroviral therapy (ART), now highly effective, safe, and simple. However, antibodies that bind the HIV envelope are able to uniquely target the virus as it seeks to enter new target cells, or as it is expressed from previously infected cells. Furthermore, the use of antibodies against HIV as
Margolis DM, Koup RA, Ferrari G.
europepmc   +5 more sources

Evaluation and diagnostic usefulness of saliva for detection of HIV antibodies: A cross-sectional study

Journal of Family Medicine and Primary Care, 2020
Background: Use of saliva as a specimen for detection of antibodies to infectious agents has generated particular interest in AIDS research community since 1980s.
Puneeta Vohra, Vikram Belkhode, Sharayu Nimonkar, Suraj Potdar, Rishabh Bhanot, Izna, Rahul Vinay Chandra Tiwari   +6 more
doaj   +3 more sources

In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice. [PDF]

Nat Biotechnol, 2022
Transplantation of B cells engineered ex vivo to secrete broadly neutralizing antibodies (bNAbs) has shown efficacy in disease models. However, clinical translation of this approach would require specialized medical centers, technically demanding ...
Nahmad AD, Lazzarotto CR, Zelikson N, Kustin T, Tenuta M, Huang D, Reuveni I, Nataf D, Raviv Y, Horovitz-Fried M, Dotan I, Carmi Y, Rosin-Arbesfeld R, Nemazee D, Voss JE, Stern A, Tsai SQ, Barzel A.   +17 more
europepmc   +2 more sources

bNAber: database of broadly neutralizing HIV antibodies. [PDF]

Nucleic Acids Res., 2013
The discovery of broadly neutralizing antibodies (bNAbs) has provided an enormous impetus to the HIV vaccine research and to entire immunology. The bNAber database at http://bNAber.org provides open, user-friendly access to detailed data on the rapidly ...
Burton, Dennis R, Butera, Sal T, Eroshkin, Alexey M, Godzik, Adam, LeBlanc, Andrew, Li, Zhanwen, Post, Kai, Rajput, Akhil, Weekes, Dana   +8 more
core   +5 more sources

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. [PDF]

Science, 2017
Xu L, Pegu A, Rao E, Doria-Rose N, Beninga J, McKee K, Lord DM, Wei RR, Deng G, Louder M, Schmidt SD, Mankoff Z, Wu L, Asokan M, Beil C, Lange C, Leuschner WD, Kruip J, Sendak R, Kwon YD, Zhou T, Chen X, Bailer RT, Wang K, Choe M, Tartaglia LJ, Barouch DH, O'Dell S, Todd JP, Burton DR, Roederer M, Connors M, Koup RA, Kwong PD, Yang ZY, Mascola JR, Nabel GJ.   +36 more
europepmc   +2 more sources

Feeding Eggs from Hens Immunized with Specific KLH-Conjugated HIV Peptide Candidate Vaccines to Chicks Induces Specific Anti-HIV gp120 and gp41 Antibodies that Neutralize the Original HIV Antigens [PDF]

Vaccine Research, 2020
Introduction: Isolation of antibodies from the egg yolk of chickens is of particular interest as a source of specific antibodies for oral administration to prevent infections and use them as immunodiagnostic reagents.
Justiz Vaillant, Ferrer Cosme, Fisher Smikle, Oliver Pérez   +3 more
doaj   +1 more source

HIV antibody testing [PDF]

BMJ, 1987
P J E Wilson, I. P Cast, K A Walters
  +15 more sources

HIV-gp140-Specific Antibodies Generated From Indian Long-Term Non-Progressors Mediate Potent ADCC Activity and Effectively Lyse Reactivated HIV Reservoir

Frontiers in Immunology, 2022
Strategies to reduce the human immunodeficiency virus (HIV) reservoir are urgently required. The antibody-dependent cellular cytotoxicity (ADCC)-mediating anti-HIV antibodies have shown an association with HIV control.
Jayshree R. Dhande, Rajani D. Bagul, Madhuri R. Thakar   +2 more
doaj   +1 more source

A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition [PDF]

, 2013
The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodies ...
Aasa-Chapman, Marlén M. I., Battella, Simone, Bonvin, Alexandre M. J. J., Davis, David, El Khattabi, Mohamed, Favier, Adrien, Forsman Quigley, Anna, Hinz, Andreas, Hock, Miriam, Hulsik, David Lutje, Langedijk, Johannes P. M., Liu, Ying-ying, Macheboeuf, Pauline, McCoy, Laura E., Poignard, Pascal, Ramos, Alejandra, Rutten, Lucy, Sabin, Charles, Seaman, Michael S., Simorre, Jean-Pierre, Strokappe, Nika M., Verrips, C. Theo, Weiss, Robin A., Weissenhorn, Winfried   +23 more
core   +19 more sources

Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition – A Nested Case-Control Study in HIV-1 Serodiscordant Couples

Frontiers in Immunology, 2022
Enveloped viruses, including the Human Immunodeficiency Virus-1 (HIV), incorporate host proteins such as human leucocyte antigens (HLA) into their envelope.
Melinda S. Suchard, Melinda S. Suchard, Neil Martinson, Neil Martinson, Susan Malfeld, Debbie de Assis Rosa, Romel D. Mackelprang, Romel D. Mackelprang, Jairam Lingappa, Jairam Lingappa, Xuanlin Hou, Helen Rees, Sinead Delany-Moretlwe, Hadassa Goldfein, Heena Ranchod, Heena Ranchod, David Coetzee, Kennedy Otwombe, Kennedy Otwombe, Lynn Morris, Lynn Morris, Caroline T. Tiemessen, Caroline T. Tiemessen, Dana M. Savulescu   +23 more
doaj   +1 more source