Demographic and Behavioural Factors in Tanzanian and Norwegian Patients with Sexually Transmitted Infections. [PDF]
To evaluate whether differences in demographic or behavioural factors might explain differences in reported or diagnosed sexually transmitted infections (STI), we have compared data from 1097 Tanzanian and Norwegian STI patients.
Chalamila, Guerino +5 more
core +1 more source
Structural Insights From HIV-Antibody Co-Evolution And Related Immunization Studies [PDF]
Human immunodeficiency virus type 1 (HIV-1) is a rapidly evolving pathogen and causes the acquired immunodeficiency syndrome (AIDS) in humans. There are ~30-35 million people infected with HIV around the world, and ~25 million have died since the first ...
Fera, Daniela +4 more
core +1 more source
Evidence for HIV-2 infection in Nepal
Assessment of the presence and prevalence of HIV-2 antibodies in patients attending the Universal College of Medical Sciences Teaching Hospital, Bhairahawa, western Nepal was done. A total of 1534 patients sera were screened for the presence of HIV-1 and
Anil Chander, V K Pahwa
doaj +1 more source
Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals. [PDF]
Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infection by HIV-1, and their elicitation may be an ...
Jorge Carrillo +8 more
doaj +1 more source
Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1 [PDF]
CD4 is the primary receptor for human immunodeficiency virus (HIV). The binding site for the surface glycoprotein of HIV type 1 (HIV-1), gp120, has been mapped to the C'-C" region of domain 1 of CD4. Previously, we have shown that a mutant of rat CD4, in
Simon, J.H.M +7 more
core +1 more source
Identification of a protein encoded in the EB-viral open reading frame BMRF2 [PDF]
Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF2 we could identify a protein-complex of 53/55 kDa in chemically induced B95-8,
A. v. Brunn +37 more
core +2 more sources
Antibody neutralization of HIV-1
Neutralizing antibodies are a major component of host defense against viruses, and appear to be particularly important in limiting the spread of cell-free virus. Results from vaccine trials in animal models suggest that these antibodies may contribute to protection against human immunodeficiency virus (HIV) infection.
Poignard, P, Klasse, P, Sattentau, Q
openaire +2 more sources
Reduced Plasma Levels of sCD14 and I-FABP in HIV-infected Patients with Mesalazine-treated Ulcerative Colitis [PDF]
BACKGROUND: Microbial translocation (MT) is a shared feature of HIV infection and inflammatory bowel disease (IBD). AIMS: This study was conducted to assess the impact of IBD (and particularly ulcerative colitis, UC) on plasma markers of MT ...
Alessandra Fantauzzi +14 more
core +1 more source
Men who have sex with men and people living with HIV are disproportionately affected in the 2022 multi-country monkeypox epidemic. The smallpox vaccine can induce cross-reactive antibodies against the monkeypox virus (MPXV) and reduce the risk of ...
Dapeng Li +14 more
doaj +1 more source
Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity
Vaccine-induced seroreactivity/positivity (VISR/P) poses a significant and common challenge to HIV vaccine implementation, as up to 95% of vaccine recipients may be misclassified as having HIV infection by current HIV screening and confirmatory ...
Ole Lagatie +12 more
doaj +1 more source

