VirologieAntibodies, and notably immunoglobulins A (IgA), are paramount in mucosal tissues as protective immune effectors against invading pathogens and immunomodulators of the microbiota. Upon human immunodeficiency virus type 1 (HIV-1) infection, systemic and mucosal IgA antibody responses are triggered.
Lorin, Valérie, Mouquet, Hugo
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Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41.
PLoS Medicine, 2008 The generation of broadly neutralizing antibodies is a priority in the design of vaccines against HIV-1. Unfortunately, most antibodies to HIV-1 are narrow in their specificity, and a basic understanding of how to develop antibodies with broad ...
Catherine A Blish +2 more
doaj +1 more source
Human immunodeficiency virus neutralizing antibodies and methods of use thereof [APPLICATION] [PDF]
, 2014 The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of ...
Bjorkman, Pamela J. +3 more
core
High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]
, 1998 A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio +11 more
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Clinics in Laboratory Medicine, 1994 This article reviews various laboratory assays for screening and detection of antibodies against HIV-1 and viral components. The prognostic role of these assays in the course of HIV-1 infection is described as well as functional aspects of anti-HIV antibodies.
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HIV-1 Superinfection in an HIV-2-Infected Woman with Subsequent Control of HIV-1 Plasma Viremia [PDF]
, 2017 A human immunodeficiency virus type 2 (HIV-2)-infected woman experienced asymptomatic superinfection with HIV-1 subtype AG. She did not have cross-neutralizing autologous HIV-1 antibodies before and shortly after HIV-1 superinfection.
Böni, Jürg +6 more
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Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]
, 2015 Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján +4 more
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Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]
, 2012 Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Amann, Kerstin Ute +7 more
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Seroepidemiology of Trichomonas vaginalis in rural women in Zimbabwe and patterns of association with HIV infection [PDF]
, 2005 Serological assays using dried blood spots from 5221 women in rural areas of eastern Zimbabwe were used to assess the epidemiology of Trichomonas vaginalis infection, and its association with HIV. Antibodies to T.
Cappuccinelli, Pietro Antonio +4 more
core
Aptamer-based therapeutics and their potential in radiopharmaceutical design [PDF]
, 2007 Aptamers, short, single stranded oligonucleotide entities, have been developed in the past 15 years against a plethora of targets and for a variety of applications.
Ferreira, Catia S. M. +1 more
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