Results 81 to 90 of about 318,673 (186)

Antibodies and Antibody Derivatives: New Partners in HIV Eradication Strategies

Frontiers in Immunology, 2018
Promptly after primoinfection, HIV generates a pool of infected cells carrying transcriptionally silent integrated proviral DNA, the HIV-1 reservoir. These cells are not cleared by combined antiretroviral therapy (cART), and persist lifelong in treated ...
Jorge Carrillo, Bonaventura Clotet, Bonaventura Clotet, Julià Blanco, Julià Blanco   +4 more
doaj   +1 more source

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection

, 2018
Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) may be directly pathogenic.
Amara, Khaled, Baeten, Dominique, Gabay, Cem, Gronwall, Caroline, Israelsson, Lena, Klareskog, Lars, Lanzavecchia, Antonio, Lloyd, Katy A., Lundberg, Karin, Lundstrom, Susanna L., Malmstrom, Vivianne, Mueller, Daniel L., Piccoli, Luca, Reed, Evan, Steen, Johanna, Titcombe, Philip J., Zhou, Diana, Zubarev, Roman A.   +17 more
core   +2 more sources

A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]

, 2016
A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul, Briggs, John AG, Cheng, Yifan, Flayhan, Ali, Frauenfeld, Jens, Garoff, Henrik, Guettou, Fatma, Jegerschöld, Caroline, Löving, Robin, Löw, Christian, Moberg, Per, Nordlund, Pär, Sonnen, Andreas F-P, Zhu, Lin   +13 more
core   +2 more sources

Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro

Scientific Reports, 2018
The importance of natural IgM antibodies in protection against infections is still emerging and these antibodies have a potential role in the maintenance of homeostasis through clearance of apoptotic bodies, complement-dependent mechanisms, inflammation ...
Claudia Devito, Rada Ellegård, Tina Falkeborn, Lennart Svensson, Mats Ohlin, Marie Larsson, Kristina Broliden, Jorma Hinkula   +7 more
doaj   +1 more source

Diagnostic Efficacy of Photostimulated Chemiluminescence Assay for Detecting Anti-HIV Antibodies: A Retrospective Study. [PDF]

Pol J Microbiol, 2023
Han J, Wang Y, Wang B, Tong H.
europepmc   +1 more source

An injectable CRISPR therapy instructs B cells to produce anti-HIV antibodies. [PDF]

Synth Biol (Oxf), 2022
Collins LT.
europepmc   +1 more source

Passive and active antibody studies in primates to inform HIV vaccines

Expert Review of Vaccines, 2018
Introduction: Prevention of infection remains the ultimate goal for HIV vaccination, and there is compelling evidence that antibodies directed to Envelope are necessary to block infection.
Ann J. Hessell, Delphine C. Malherbe, Nancy L. Haigwood   +2 more
doaj   +1 more source

The impact of antibodies to human glycoprotein CD4 and gamma-interferon on the t-cell immunity and the cytokine levels in patients co-infected with HIV/HCV during the antiretroviral therapy

Медицинский вестник Юга России, 2017
Objective: This work was to estimate the influence of antibodies to human glycoprotein CD4 and IFN-γ on the T-cell immunity and the cytokine levels in patients with HIV and HIV/HCV during the standard antiretroviral therapy.
A. V. Strygin, A. M. Docenko, A. O. Strygina, E. I. Morkovin, V. I. Petrov   +4 more
doaj   +1 more source

Combination anti-HIV antibodies provide sustained virological suppression. [PDF]

Nature, 2022
Sneller MC, Blazkova J, Justement JS, Shi V, Kennedy BD, Gittens K, Tolstenko J, McCormack G, Whitehead EJ, Schneck RF, Proschan MA, Benko E, Kovacs C, Oguz C, Seaman MS, Caskey M, Nussenzweig MC, Fauci AS, Moir S, Chun TW.   +19 more
europepmc   +1 more source

Enhancing antibodies in HIV infection

Parasitology, 1997
The author has summarized the history of discovery, the mechanism and the clinical significance of antibody-dependent enhancement (ADE) of HIV infection. ADE has two major forms: (a) complement-mediated antibody-dependent enhancement (C-ADE) and (b) complement-independent Fc receptor-dependent ADE (FcR-ADE).
openaire   +2 more sources