AIDS Research and Therapy, 2021 Background An increasing number of HIV cure trials involve combining multiple potentially curative interventions. Until now, considerations for designing and implementing complex combination HIV cure trials have not been thoroughly considered. Methods We
Karine Dubé +8 more
doaj +1 more source
A new paradigm evaluating cost per cure of HCV infection in the UK [PDF]
, 2016 Background: New interferon (IFN)-free treatments for hepatitis C are more effective, safer but more expensive than current IFN-based therapies. Comparative data of these, versus current first generation protease inhibitors (PI) with regard to costs and ...
Aline Gauthier +7 more
core +2 more sources
Journal of Virus Eradication, 2020 Objective: Little is known about willingness among people living with HIV (PLHIV) to participate in HIV cure research in the Netherlands. We compared results of a cross-sectional questionnaire assessing hypothetical willingness to actual willingness ...
Henrieke A.B. Prins +4 more
doaj +1 more source
So Pathogenic or So What?—A Brief Overview of SIV Pathogenesis with an Emphasis on Cure Research
Viruses, 2022 HIV infection requires lifelong antiretroviral therapy (ART) to control disease progression. Although ART has greatly extended the life expectancy of persons living with HIV (PWH), PWH nonetheless suffer from an increase in AIDS-related and non-AIDS ...
Adam J. Kleinman +2 more
doaj +1 more source
Integrating Community-Based Interventions to Reverse the Convergent TB/HIV Epidemics in Rural South Africa. [PDF]
, 2015 The WHO recommends integrating interventions to address the devastating TB/HIV co-epidemics in South Africa, yet integration has been poorly implemented and TB/HIV control efforts need strengthening.
Brooks, Ralph P +7 more
core +3 more sources
Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]
, 2015 Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric +14 more
core +2 more sources
HIV cure research: print and online media reporting in Australia
Journal of Virus Eradication, 2017 Objectives: While still in its early stages, recent scientific research towards a cure for HIV has generated widespread media interest. The aim of this paper was to explore the ways in which this research has been represented in Australian print and ...
Jennifer Power +10 more
doaj +1 more source
Geoadditive Latent Variable Modelling of Count Data on Multiple Sexual Partnering in Nigeria [PDF]
, 2009 The 2005 National HIV/AIDS and Reproductive Health Survey in Nigeria provides evidence that multiple sexual partnering increases the risk of contracting HIV and other sexually transmitted diseases.
Adebayo, Samson B. +2 more
core +2 more sources
Can a pill prevent HIV? Negotiating the biomedicalisation of HIV prevention [PDF]
, 2015 This article examines how biomedicalisation is encountered, responded to and negotiated within and in relation to new biomedical forms of HIV prevention.
Flowers, Paul +2 more
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source