Results 121 to 130 of about 25,017 (220)

Stereochemistry of Polypeptide Conformation in Coarse Grained Analysis

, 2013
The conformations available to polypeptides are determined by the interatomic forces acting on the peptide units, whereby backbone torsion angles are restricted as described by the Ramachandran plot.
Hendrickson, Wayne A, Korkut, Anil
core   +1 more source

HbAHP-25, an In-Silico Designed Peptide, Inhibits HIV-1 Entry by Blocking gp120 Binding to CD4 Receptor.

PLoS ONE, 2015
Human Immunodeficiency Virus (HIV-1) poses a serious threat to the developing world and sexual transmission continues to be the major source of new infections.
Tahir Bashir, Mandar Patgaonkar, Selvaa C Kumar, Achhelal Pasi, Kudumula Venkata Rami Reddy   +4 more
doaj   +1 more source

Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice. [PDF]

, 2019
Mounting evidence suggests that antiretroviral therapy (ART) drugs may contribute to the prevalence of HIV-associated neurological dysfunction. The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial ...
Achim, Cristian L, Calcutt, Nigel A, Carson, Aliyah, Ellis, Ronald J, Fields, Jerel Adam, Frizzi, Katie, Han, May Madi, Lindsay, Charmaine, Murphy, Anne, Sambhwani, Shrey, Soontornniyomkij, Benchawanna, Swinton, Mary K   +11 more
core  

Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. [PDF]

, 2020
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells.
Amara, Rama R, Beck, Zoltan, Dinasarapu, Ashok R, Elizaldi, Sonny R, Foehl, David H, Forthal, Donald N, Gach, Johannes S, Iyer, Smita S, Kozlowski, Pamela A, LaBranche, Celia C, Lakshmanappa, Yashavanth Shaan, Matyas, Gary R, Nguyen, Nancy K, Rane, Niharika N, Rao, Mangala, Reimann, Keith A, Schmidt, Brian A, Shen, Xiaoying, Tomaras, Georgia D, Trinh, Hung V, Verma, Anil, Walter, Korey A   +21 more
core  

Evaluating the neutralizing antibody response to HIV-1 membrane proximal external regional; Implications for vaccine design [PDF]

, 2014
Includes bibliographical references.Inducing broadly neutralizing antibodies targeting the HIV-1 envelope is thought to be crucial for developing an effective vaccine.
Jacob, Rajesh Abraham
core  

HIV-1 envelope protein gp120. Glycovirology of the V3 loop

, 2000
The human immunodeficiency virus type 1 (HIV-1) infection usually is lethal as a consequence of the acquired immunodeficiency syndrome (AIDS). HIV-1 is an enveloped virus and the trimeric envelope glycoprotein complex, gp120/gp41, is responsible for binding of the virus both to the primary cellular receptor CD4 and the coreceptors, CXCR4 and CCR5 ...
openaire  

Antiretroviral effect of 4-thio-uridylate against human immunodeficiency virus type 1 [PDF]

, 2012
Albert J., Barbouche R., Beck Z., Berger E. A., Clapham P., Cox S., Doms R. W., Einfeld D., Fenouillet E., Horváth A., Horváth A., Joseph Ongrádi, Juhász E., Kanizsai S., Kanizsai Sz., Kemény B., Kilby J. M., Károly Nagy, Leonard C., Markovic I., Matthias L. J., Nagy K., Nagy K., Nagy K., Nisole S., Ou W., Ryser H. J., Szatmari I., Szilvia Kanizsai, Tarkanyi I., Tõkés S., Wittinghoff E., Ágoston Ghidán   +32 more
core   +1 more source

HIV Envelope Protein gp120 [PDF]

, 2020
openaire   +1 more source

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

Journal of Translational Medicine, 2010
It is well established that HIV-1 infection typically involves an interaction between the viral envelope protein gp120/41 and the CD4 molecule followed by a second interaction with a chemokine receptor, usually CCR5 or CXCR4.
Cicala Claudia, Arthos James, Fauci Anthony   +2 more
doaj  

Galectin-8 binds HIV envelope glycoproteins with high affinity and promotes viral infectivity. [PDF]

Front Cell Infect Microbiol
Sheik-Khalil E, Kahl-Knutson B, Johansson E, Karlson S, Nilsson UJ, Leffler H, Jansson M.   +6 more
europepmc   +1 more source