Results 191 to 200 of about 25,017 (220)
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7‐Chlorokynurenate Ameliorates Neuronal Injury Mediated by HIV Envelope Protein gp120 in Rodent Retinal Cultures

European Journal of Neuroscience, 1992
AbstractPrior studies with in vitro model systems have suggested that at least part of the neurological manifestations of AIDS may stem from neuronal injury involving the HIV‐1 coat protein gp120. This form of neuronal damage is most probably mediated indirectly by a complex set of cellular interactions among macrophages, astrocytes, and neurons ...
openaire   +2 more sources

HIV-1 envelope protein gp120 impairs intracellular antifungal mechanisms in human monocytes.

1998
The key to success of fungal opportunistic pathogens in the immunocompromised host is related to survival inside phagocytic cells, which represent the first line of defense against microorganisms. The contribution of human immunodeficiency virus-1 recombinant envelope protein gp120 on effector functions of peripheral blood monocytes (PBM) against ...
PIETRELLA, Donatella   +5 more
openaire   +1 more source

The HIV Envelope Protein gp120 in the Nervous System

Biochemical Pharmacology, 1998
M.Tiziana Corasaniti   +3 more
openaire   +1 more source

Global and Local Structural Properties of the Principal Neutralizing Determinant of the HIV-1 Envelope Protein gp120

Journal of Biomolecular Structure and Dynamics, 1999
The model of spatial structure for the principal neutralizing determinant (PND) of the HIV-1 envelope protein gp120 is proposed in terms of two-dimensional nuclear Overhauser effect (NOE) spectroscopy data. To build the model, the NMR-based theoretical conformational analysis of synthetic PND peptides of length 40, 24, and 12 residues is carried out ...
openaire   +2 more sources

V3 loop region of the HIV-1 gp120 envelope protein is essential for virus infectivity.

Virology, 1992
The mechanism by which HIV-1 mediates cell fusion and penetrates target cells, subsequent to receptor (CD4) binding, is not well understood. However, neutralizing antibodies, which recognize the principal neutralizing determinants of the gp120 envelope protein (the V3 loop region, residues 296 to 331), have been shown to effectively block cell fusion ...
L A, Ivanoff   +8 more
openaire   +1 more source

HIV-1 gp120 envelope protein and morphine-tubular cell interaction products modulate kidney fibroblast proliferation.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1998
Renal interstitial scarring is an important feature of HIV-associated nephropathy. Intravenous drug abuse has been demonstrated to be a risk factor for the development of HIV-associated nephropathy in patients with HIV infection. We studied the effect of tubular cell-morphine and/or HIV-1 gp120 envelope protein interaction products on kidney fibroblast
P C, Singhal   +5 more
openaire   +1 more source

Vaccine Efficacy of ALVAC-HIV and Bivalent Subtype C gp120–MF59 in Adults

New England Journal of Medicine, 2021
Glenda Gray   +2 more
exaly  

[Interaction of HIV envelope protein gp120 with receptor CD4].

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1992
K, Ohki, T, Kimura, K, Ikuta
openaire   +1 more source

The antigenic structure of the HIV gp120 envelope glycoprotein

Nature, 1998
Richard T Wyatt   +2 more
exaly  

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