Results 221 to 230 of about 34,307 (290)

Advancements in development of novel class of HIV protease inhibitors. [PDF]

Ann Med
Gu WG, Yin GZ, Zhang YP.
europepmc   +1 more source

Mitochondrial DNA damage in HIV infection: a mechanistic driver of immunometabolic dysfunction and chronic inflammation. [PDF]

Front Immunol
Ma L, Wang X, Xu H.
europepmc   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Albuvirtide plus 3BNC117 provides a promising combination strategy for multidrug-resistant HIV-1 infection: a prospective, open-label, multicenter phase 2 trial. [PDF]

BMC Infect Dis
Zhou Y, Qin Y, Liu X, Zhao Q, Wang M, Chen Y, Li Y, He K, Li X, Harypursat V, Xie D, Chen Y.   +11 more
europepmc   +1 more source

Understanding Risky Behaviors Among Fishers in a Lower Middle Income Country: A Qualitative Study of Fishers in Elmina, Ghana

Public Health Challenges, Volume 5, Issue 2, June 2026.
Fishers in Elmina, Ghana, engage in alcohol use, smoking, and unsafe sexual practices shaped by mobility, economic pressures, and risk perceptions. Using risk compensation theory, this study shows how occupational risk normalizes health risk‐taking, highlighting the need for integrated behavioral and structural interventions in fishing communities ...
Sylvester Kyei‐Gyamfi, Frank Kyei‐Arthur, Bismark Bless Nyadzi, Oppong Kwarteng Hammond, Eunice Kisiwaa Gyan, Joha Issaka Braimah   +5 more
wiley   +1 more source

Autophagy in emerging and highly concerned severe zoonotic infectious diseases. [PDF]

Front Immunol
Qi Y, Wang L, Wu S, Meng C, Chu Y, Yin Y, Jiao H.   +6 more
europepmc   +1 more source

Thiazolidinedione–Pyrazolopyrimidinone Molecular Hybrids With Alkyl Spacers: Potential Antitubercular Agents Complemented by Molecular Modeling

ChemistrySelect, Volume 11, Issue 24, 25 June 2026.
We report the synthesis of 21 novel thiazolidinedione–pyrazolopyrimidinone derivatives (12a–u), prepared by coupling thiazolidinedione and pyrazolopyrimidinone pharmacophores through various alkyl linkers. The compounds were characterized spectroscopically and evaluated against the Mtb H37Rv strain, identifying compounds 5c and 5d as potent ...
Pule Seboletswe, Gobind Kumar, Nontobeko Gcabashe, Sanjeev Dhawan, Neha Manhas, Ankit, Audrey Jordaan, Digby F. Warner, Parvesh Singh   +8 more
wiley   +1 more source

Identification and structure-activity relationship analysis of minimal fusion inhibitors targeting measles virus F protein. [PDF]

RSC Med Chem
Kobayashi K, Yamaguchi Y, Itahara M, Hirata K, Aoki K, Iwamoto N, Hayashi H, Kodama E, Oishi S.   +8 more
europepmc   +1 more source

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

Small, Volume 22, Issue 33, 12 June 2026.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito, Mariana B. Oliveira, João F. Mano   +2 more
wiley   +1 more source

Nanobodies: A Promising Toolkit for Diagnostic Applications

SmartMat, Volume 7, Issue 3, June 2026.
This review focuses on camelid‐derived nanobodies (VHHs) and explains how their small size and high stability support robust diagnostic design. Applications across ELISA, lateral flow assays, and PET/SPECT imaging are summarized, along with clinical progress such as caplacizumab.
Wei Wu, Abid Ali, Li Sun, Jiahao Hu, Lina Hameed, Saba Shafi, Ali Raza, Khuzin Dinislam, Wenjing Xing, Long Rong, Jie Lin, Jian Ma   +11 more
wiley   +1 more source