Results 131 to 140 of about 45,597 (259)

HIV integrase [PDF]

Science-Business eXchange, 2008
openaire   +3 more sources

Is Resistance to Dolutegravir Possible When This Drug Is Used in First-Line Therapy?

Viruses, 2014
Dolutegravir (DTG) is an HIV integrase inhibitor that was recently approved for therapy by the Food and Drug Administration in the United States. When used as part of first-line therapy, DTG is the only HIV drug that has not selected for resistance ...
Thibault Mesplède, Mark A. Wainberg
doaj   +1 more source

A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection. [PDF]

Retrovirology, 2022
Zhao AV, Crutchley RD, Guduru RC, Ton K, Lam T, Min AC.   +5 more
europepmc   +1 more source

Scientific Opinion on the tolerable upper intake level for supplemental docosahexaenoic acid

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract Following a request from the European Commission, the Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the revision of the safe level of intake for supplemental docosahexaenoic acid (DHA).
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, Angeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Frank Thies, Alfonso Siani, Ionut Craciun, Silvia Valtueña Martínez   +17 more
wiley   +1 more source

First report of computational protein-ligand docking to evaluate susceptibility to HIV integrase inhibitors in HIV-infected Iranian patients. [PDF]

Biochem Biophys Rep, 2022
Ghasabi F, Hashempour A, Khodadad N, Bemani S, Keshani P, Shekiba MJ, Hasanshahi Z.   +6 more
europepmc   +1 more source

Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization. [PDF]

, 2018
Lentiviral vector mobilization following HIV-1 infection of vector-transduced cells poses biosafety risks to vector-treated patients and their communities.
Bi, Yanmin, Fry, Nate J, Hu, Peirong, Kafri, Tal, Kohn, Donald B, Ma, Hong, Suwanmanee, Thipparat, Zeithaml, Brian   +7 more
core  

From ligand to complexes: inhibition of HIV-1 Integrase by beta-diketo acid metal complexes [PDF]

, 2006
Recently, a class of compounds bearing a β-diketo acid moiety have emerged as the most promising lead in anti-HIV-1 IN drug discovery. It is believed that the β-diketo acid pharmacophoric motif could be involved in a functional sequestration of one or ...
Al-Mawsawi, Laith Q., Bacchi, Alessia, Carcelli, Mauro, Derudas, Marco, Fisicaro, Emilia, Gates, Paul, Neamati, Nouri, Rogolino, Dominga, Sechi, Mario   +8 more
core  

No association between use of tenofovir disoproxil fumarate, etravirine, or integrase-strand transfer inhibitors and acquisition or severe outcomes of SARS-CoV-2 infection in people with HIV in the Netherlands

, 2023
Myrthe L. Verburgh, Marc van der Valk, Bart Rijnders, Peter Reiss, Ferdinand W.N.M. Wit   +4 more
openalex   +1 more source

Halogen Bonding in Nucleic Acid Complexes

, 2017
Halogen bonding (X-bonding) has attracted notable attention among noncovalent interactions. This highly directional attraction between a halogen atom and an electron donor has been exploited in knowledge-based drug design. A great deal of information has
Kolář, Michal H., Tabarrini, Oriana
core   +1 more source

Designing potential HIV-1 integrase inhibitors: An In silico approach

, 2021
Arif Mermer
openalex   +2 more sources