Results 11 to 20 of about 18,464 (76)

Assessing weight change in adolescents and young adults with perinatally acquired HIV and integrase inhibitor use

HIV Medicine, EarlyView.
Abstract Introduction Integrase strand transfer inhibitors (INSTIs) are the mainstay of treatment in adults and children living with HIV. Weight gain has been associated with INSTI use in adults; however, less data exist on its effects on younger patients.
Kathleen J. Pincus, Nabila Faridi, Patrick Amadeus Ryscavage, Hyunuk Seung, Kristine A. Parbuoni, Matthew Grant, Neha Sheth Pandit   +6 more
wiley   +1 more source

Rethinking HIV treatment: How non‐integrase strand regimens may hold the key to better immune health

HIV Medicine, EarlyView.
Abstract Purpose HIV outcome changed drastically with antiretroviral (ARV) therapy, especially after the introduction of second‐generation integrase strand transfer inhibitors (INSTIs). Despite these advances, however, chronic immune activation and exhaustion, marked by programmed cell death 1 (PD‐1) and programmed death ligand 1 (PD‐L1) upregulation ...
Bogusz Aksak‐Wąs, Karolina Skonieczna‐Żydecka, Miłosz Parczewski, Rafał Hrynkiewicz, Filip Lewandowski, Karol Serwin, Kaja Mielczak, Franciszek Lenkiewicz, Paulina Niedźwiedzka‐Rystwej   +8 more
wiley   +1 more source

Late diagnosis of HIV among Ukrainian refugees in the Czech Republic: A retrospective, observational study

HIV Medicine, EarlyView.
Abstract Objectives This retrospective, observational, non‐interventional study describes the demographics, characteristics, immunological and virological status, coinfections, healthcare unit of HIV diagnosis and follow‐up status of Ukrainian refugees with newly diagnosed HIV in the Czech Republic, with a special focus on those with a late HIV ...
Zofia Bartovská, Ricardo Massmann, David Jilich, Tomáš Groh, Lukáš Fleischhans, Milan Zlámal, Radek Svačinka, David Vydrář, Dalibor Sedláček, Miroslav Kubiska, Jaroslav Kapla, Lucie Nepovímová, Daniela Bartková, Lenka Olbrechtová, Zdeňka Jerhotová, Eva Novotná, Jakub Wnuk, Vratislav Němeček, Pavel Dlouhý, Štěpán Cimrman, Marek Malý   +20 more
wiley   +1 more source

Weight gain, obesity, and the impact of lifestyle factors among people living with HIV: A systematic review

Obesity Reviews, EarlyView.
Summary HIV remains a significant health concern, but the advent of antiretroviral therapy (ART) has transformed it into a manageable chronic condition. However, weight gain and obesity pose a substantial challenge for people living with HIV (PLWH). Moreover, the role of lifestyle has not yet been comprehensively investigated.
Giulia Gilberti, Giorgio Tiecco, Silvia Marconi, Monica Marullo, Barbara Zanini, Eugenia Quiros‐Roldan   +5 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Latest Progress on Tuberculosis and HIV Co‐Infection: A Closer Look at People of Different Ages

Advanced Therapeutics, Volume 8, Issue 4, April 2025.
Tackling the problem of tuberculosis (TB) and human immunodeficiency virus (HIV) co‐infection is a serious global health concern affecting people of all ages. This review presents the characteristics of both diseases, current treatment and diagnostic guidelines, associated problems, innovations in disease management, and overall effects on global ...
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
wiley   +1 more source

HIV and Non‐HIV Patients Have Similar Rates of Neoplastic Findings on Screening Colonoscopy Within a Predominantly African American Cohort

Cancer Medicine, Volume 14, Issue 8, April 2025.
ABSTRACT Introduction With the reduction in human immunodeficiency virus (HIV)–related mortality secondary to antiretroviral therapy, chronic medical conditions and age‐related cancers account for a larger proportion of mortality among those with HIV. Cancer risk overall remains elevated in HIV patients, and cancer screening data in this population is ...
Pooja Mude, Alexandra E. Thomson, Lavannya Atri, Samantha Newman, Carlos Palacio, John Erikson L. Yap, Christian S. Jackson, Kenneth J. Vega   +7 more
wiley   +1 more source

Addressing Cardiometabolic Challenges in HIV: Insights, Impact, and Best Practices for Optimal Management—A Narrative Review

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Introduction Since the advent of highly active antiretroviral therapy (HAART), morbidity and mortality rates associated with human immunodeficiency virus (HIV) have significantly decreased leading to prolonged life span of Individuals living with HIV due to the effectiveness of antiretroviral therapy.
Nadine Mugisha, Laura Ghanem, Omar A. I. Komi, Rawan Noureddine, Sanobar Shariff, Magda Wojtara, Mahlagha Mousavi Nanehkeran, Olivier Uwishema   +7 more
wiley   +1 more source

Differences in clinical characteristics between adolescents and young adults with perinatally and sexually acquired HIV in the Asia‐Pacific region

Journal of the International AIDS Society, Volume 28, Issue 4, April 2025.
Abstract Introduction We assessed the long‐term HIV‐related health outcomes of young adults with perinatally acquired HIV (PHIV) compared with those who acquired HIV through sexual transmission in the Asia‐Pacific region. Methods We conducted a cross‐sectional study using data from three paediatric and adult cohorts within the International ...
Phatharajit Phatharodom, Alan Maleesatharn, Tavitiya Sudjaritruk, Suwimon Khusuwan, Kathy Petoumenos, Linda Aurpibul, Romanee Chaiwarith, Michelle L. Giles, Du Tuan Quy, Smita Nimkar, Alvina Widhani, Junko Tanuma, Matthew Law, Annette H. Sohn, Kulkanya Chokephaibulkit, IeDEA Asia‐Pacific   +15 more
wiley   +1 more source

Phenotypic Characterization of Replication‐Impaired Lenacapavir‐Resistant HIV Clinical Isolates

Journal of Medical Virology, Volume 97, Issue 4, April 2025.
ABSTRACT Lenacapavir (LEN) is a potent, first‐in‐class long‐acting HIV‐1 capsid (CA) inhibitor, approved for treatment of people with multi‐drug resistant HIV in combination with other antiretrovirals. In clinical studies with LEN, the CA resistance‐associated mutations (RAMs) M66I, Q67H/K/N, K70H/N/R/S, N74D/H/K, A105S/T, and T107A/C/N/S were observed.
Sally Demirdjian, Vidula Naik, Nicolas Margot, Brie Falkard, Christian Callebaut   +4 more
wiley   +1 more source