HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase [PDF]
, 2000 Amy S. Espeseth +11 more
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Twenty-six years of HIV science: an overview of anti-HIV drugs metabolism
Brazilian Journal of Pharmaceutical Sciences, 2011 From the identification of HIV as the agent causing AIDS, to the development of effective antiretroviral drugs, the scientific achievements in HIV research over the past twenty-six years have been formidable.
Carolina Horta Andrade +2 more
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The strand transfer oligonucleotide inhibitors of HIV-integrase
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008 Retroviral integrase participates in two catalytic reactions, which require interactions with the two ends of the viral DNA in the 3'processing reaction, and with a targeted host DNA in the strand transfer reaction. The 3'-hydroxyl group of 2'-deoxyadenosine resulting from the specific removing of GT dinucleotide from the viral DNA in the processing ...
Jan Snášel +3 more
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HIV-1 Protease Inhibitors From Marine Brown Alga: A Literature Review [PDF]
, 2017 The human immunodeficiency virus type 1 (HIV-1) causes an infectious disease that if left untreated can progress to acquired immunodeficiency syndrome (AIDS) and be fatal.
Nunez Aguilar, Eric
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Caffeoylquinic acids as inhibitors for HIV-I protease and HIV-I integrase: a molecular docking study [PDF]
, 2016 Caffeoylquinic acids are ubiquitous phenolic compounds with several health benefits to humans and they have been shown to be promisinganti-HIV compounds.
Castilho, Paula C. +2 more
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Discovery of a small-molecule HIV-1 integrase inhibitor-binding site [PDF]
, 2006 Laith Q. Al‐Mawsawi +6 more
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Novel HIV Integrase Inhibitors with Anti-HIV Activity: Insights into Integrase Inhibition from Docking Studies [PDF]
, 2006 Arthur G. Cox, Vasu Nair
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A Review of Electroanalytical Techniques for Determination of Anti-HIV Drugs
International Journal of Electrochemistry, 2011 Until now after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti-HIV compounds have been formally approved for clinical use in the treatment of ...
Burçin Bozal +2 more
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Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part II. Integrase inhibition [PDF]
, 2007 Sylvia Lee‐Huang +8 more
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Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS
HIV/AIDS: Research and Palliative Care, 2014 Krishan K PandeyInstitute for Molecular Virology, Saint Louis University Health Sciences Center, St Louis, MO, USAAbstract: Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors belong to a novel class of antiretroviral drugs with high potency
Pandey KK
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