Results 141 to 150 of about 71,892 (273)

Single amino acid substitution in HIV‐1 integrase catalytic core causes a dramatic shift in inhibitor selectivity [PDF]

, 2007
Laith Q. Al‐Mawsawi, Mario Sechi, Nouri Neamati   +2 more
openalex   +1 more source

Analysis of a Stochastic Predator-Prey Model with Applications to Intrahost HIV Genetic Diversity [PDF]

arXiv, 2009
During an infection, HIV experiences strong selection by immune system T cells. Recent experimental work has shown that MHC escape mutations form an important pathway for HIV to avoid such selection. In this paper, we study a model of MHC escape mutation.
arxiv  

Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS

HIV/AIDS: Research and Palliative Care, 2014
Krishan K PandeyInstitute for Molecular Virology, Saint Louis University Health Sciences Center, St Louis, MO, USAAbstract: Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors belong to a novel class of antiretroviral drugs with high potency
Pandey KK
doaj  

Changes to the HIV Long Terminal Repeat and to HIV Integrase Differentially Impact HIV Integrase Assembly, Activity, and the Binding of Strand Transfer Inhibitors [PDF]

, 2007
Ira B. Dicker, Himadri Samanta, Zhufang Li, Yang Hong, Yuan Tian, Jacques Banville, Roger Rémillard, Michael Walker, David R. Langley, Mark Krystal   +9 more
openalex   +1 more source

Research on Cumin Peptides Using PBS Extraction and Their Multifunctional Bioactivities [PDF]

arXiv
This study employed neutral PBS buffer combined with ammonium sulfate fractionation to isolate peptide-active fractions (PD-30, PD-50, PD-80) from Cuminum cyminum L.seeds (cumin) and systematically evaluated their antimicrobial, antioxidant, hypoglycemic, and anticancer activities.
arxiv  

Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part II. Integrase inhibition [PDF]

, 2007
Sylvia Lee‐Huang, Philip Lin Huang, Dawei Zhang, Jae Wook Lee, Ju Bao, Yongtao Sun, Young‐Tae Chang, John H. Zhang, Paul L. Huang   +8 more
openalex   +1 more source

From protease inhibitors to integrase strand transfer inhibitors: the evolution of HIV drug resistance management

Zhongguo linchuang yanjiu
Antiretroviral therapy (ART) has significantly improved the prognosis of HIV/AIDS patients and has become an important global strategy for the prevention and control of AIDS.
HU Zhiliang, YANG Yongfeng
doaj   +1 more source

Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue [PDF]

, 2007
Christine Fossey, Ngoc Trinh Huynh, Anh-Hoang Vu, Anamaria Vidu, Irina Zarafu, D. LADUREE, Sylvie Schmidt, Géraldine Laumond, Anné-Marie Aubertin   +8 more
openalex   +1 more source

HIV-1 Integrase Inhibitors: A Comparative Review of Efficacy and Safety

Drugs, 2020
K. Scarsi, Joshua P Havens, A. Podany, Sean N. Avedissian, C. Fletcher   +4 more
semanticscholar   +1 more source

Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance [PDF]

, 2009
M. Tschochner, Abha Chopra, T. Maiden, Imran F Ahmad, Ian James, Hansjakob Furrer, Huldrych F. Günthard, S. Mallal, Andri Rauch, Mina John   +9 more
openalex   +1 more source