Results 191 to 200 of about 32,363 (272)

Harziachalasins A-G, polycyclic-fused cytochalasins from the endophytic fungus Trichoderma harzianum MLJ-4 with HIV latency reversal activity. [PDF]

Nat Prod Bioprospect
Zhang YJ, Yang XY, Fu YF, Liao Q, Chen JQ, Chen XA, Huang D, Yuan T, Chen X, Yin S, Tang GH.   +10 more
europepmc   +1 more source

Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus‐Associated Disorders

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Kaposi sarcoma herpes virus (KSHV) is associated with multiple clinical manifestations, including primary effusion lymphoma, an aggressive CD38+ B cell lymphoma with a plasmablastic phenotype. Case This case describes an antiretroviral therapy‐adherent person with HIV who presented with concurrent KSHV‐related disorders of Kaposi ...
Kandice Roberts, Paula Valiño Ramos, Saurabh Jindal, Vikas Prasad, Yi Shan Lee, Mariam Khanfar, Obi L. Griffith, Malachi Griffith, Jeanne Jiang, Ethel Cesarman, Daniel Rauch, Paul Simonson, Thomas Odeny, Lee Ratner   +13 more
wiley   +1 more source

Thymosin α1-induced secretion of the IL-15/RA complex by THP-1-derived dendritic cells restrains HIV latency <i>in vitro</i>. [PDF]

Virulence
Chen C, Xun J, Wang J, Zhang R, Qi T, Liu L, Zhang X, Song Z, Shen Y, Lu H, Chen J.   +10 more
europepmc   +1 more source

Isoform-Selective Versus Nonselective Histone Deacetylase Inhibitors in HIV Latency Reversal. [PDF]

AIDS Res Hum Retroviruses, 2022
Boateng AT, Abaidoo-Myles A, Bonney EY, Kyei GB.   +3 more
europepmc   +1 more source

Regulation of HIV-1 latency by basal transcription

, 2013
HIV/AIDS is undoubtedly one of mankind’s most pressing health concerns. Currently, there are ~34 million people infected worldwide, with ~3 million new infections and ~2 million deaths every year.
Dahabieh, Matthew Solomon
core  

Hydrogen Sulfide Rescues Microglia From HIV Tat‐Driven Ferroptosis: Implications for HIV‐Associated Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
HIV Tat induces ferroptosis and proinflammatory activation in microglia through iron accumulation and oxidative stress. Hydrogen sulfide donor NaHS suppresses HIV Tat‐induced ferroptosis by restoring redox balance, reinforcing the SLC7A11‐GPX4 axis, and attenuating microglial inflammation, highlighting hydrogen sulfide as a potential therapeutic ...
Aitizaz Ul Ahsan, Frida L. Martínez‐Cuevas, Elias Horanieh, Seema Singh, Uma Maheswari Deshetty, Palsamy Periyasamy, Shilpa Buch   +6 more
wiley   +1 more source

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1514-1521, June 2026.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld, Geetha S. Iyer, Suna C. Seo, Andrew Giffin, Andrew L. Simon, Sheryl A. Kluberg, Emma R. Hoffman, Jamal T. Jones, Sarah K. Dutcher, Joyce A. Korvick   +9 more
wiley   +1 more source

Efficient mRNA delivery to resting T cells to reverse HIV latency. [PDF]

Nat Commun
Cevaal PM, Kan S, Fisher BM, Moso MA, Tan A, Liu H, Ali A, Tanaka K, Shepherd RA, Kim Y, Ong J, Furtado DL, Holz M, Purcell DFJ, Casan JML, Payne T, Zhao W, Fareh M, McMahon JH, Deeks SG, Hoh R, Telwatte S, Pouton CW, Johnston APR, Caruso F, Symons J, Lewin SR, Roche M.   +27 more
europepmc   +1 more source

Access to diagnosis using liquid biopsy (ADLiB): Identifying lymphoma in a tuberculosis‐endemic setting

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract In HIV‐ and tuberculosis (TB)‐endemic regions, lymphoma diagnosis is often delayed because symptoms can overlap with TB, and access to biopsy and specialized pathology is limited. To address this, we developed and internally evaluated the Access to Diagnosis using Liquid Biopsy (ADLiB) platform—a plasma cell‐free DNA (cfDNA)‐based approach ...
Katherine Antel, Nina Xiong, Mwanasha Merrill, Taiyang Chen, Lauren McGrath, Clara Droessler, Maxine van der Schyff, Meng‐Xuan Wu, Dylan Cheddie, Charlotte Slome, Liam McBride, Jonathan Day, Zainab Mohamed, Nazia Fakie, Nomonde Mbatani, Charlotte Shultz, Graeme Meintjes, Svitlana Tyekucheva, Elizabeth F. Cohen, Michael Y. Tolstorukov, Estelle Verburgh, Mark A. Murakami   +21 more
wiley   +1 more source

The intestinal interferon system and specialized enterocytes as putative drivers of HIV latency. [PDF]

Front Immunol
Creighton RL, Hughes SM, Hladik F, Gornalusse GG.   +3 more
europepmc   +1 more source