Results 171 to 180 of about 32,363 (272)

Discovering the Mechanisms of Oleodaphnone as a Potential HIV Latency-Reversing Agent by Transcriptome Profiling. [PDF]

Int J Mol Sci, 2023
Li S, Wang X, Yang Y, Wu X, Zhang L.
europepmc   +1 more source

The role of VIF in overcoming the APOBEC3G block to HIV-1 replication [PDF]

This project focuses on the Virus Infectivity Factor protein of HIV-1 and its relief of the block to virus replication exerted by the APOBEC3G component of the innate immune response.
Kulkarni, Anurag
core  

Examining bidirectional longitudinal relationships between physical activity and physical function in older breast cancer survivors: The Thinking and Living with Cancer study

Cancer, Volume 132, Issue 12, 15 June 2026.
Abstract Background Older breast cancer survivors are susceptible to cancer‐ and treatment‐related losses in physical function that can negatively affect daily living activities, mobility, and independence. Although physical activity can improve physical function, few studies have focused on older survivors or explored interrelationships between ...
Ashley L. Artese, Xingtao Zhou, Brent J. Small, Tim A. Ahles, Jaeil Ahn, Traci N. Bethea, Chloe C. Casagrande, Eunji Choi, Harvey J. Cohen, Martine Extermann, Deena Graham, Katherine Hall, Claudine Isaacs, Heather S. L. Jim, Cynthia D. J. Kusters, Brenna C. McDonald, Zev M. Nakamura, Sunita K. Patel, Kelly E. Rentscher, James C. Root, Andrew J. Saykin, Kathleen Van Dyk, Wanting Zhai, Judith E. Carroll, Jeanne Mandelblatt   +24 more
wiley   +1 more source

Targeting NF-κB signaling for HIV latency reversal: Mechanisms, challenges, and therapeutic perspectives. [PDF]

Virus Res
Shirazi MMA, Sadat SM.
europepmc   +1 more source

Innate immune regulation in HIV latency models. [PDF]

Retrovirology, 2022
Olson RM, Gornalusse G, Whitmore LS, Newhouse D, Tisoncik-Go J, Smith E, Ochsenbauer C, Hladik F, Gale M.   +8 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, Volume 16, Issue 6, Page 1132-1141, June 2026.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

HIV Latency in Myeloid Cells: Challenges for a Cure. [PDF]

Pathogens, 2022
Chitrakar A, Sanz M, Maggirwar SB, Soriano-Sarabia N.   +3 more
europepmc   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, Volume 99, Issue 6, Page 1468-1479, June 2026.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

HSV-2 triggers upregulation of MALAT1 in CD4+ T cells and promotes HIV latency reversal. [PDF]

J Clin Invest, 2023
Pierce CA, Loh LN, Steach HR, Cheshenko N, Preston-Hurlburt P, Zhang F, Stransky S, Kravets L, Sidoli S, Philbrick W, Nassar M, Krishnaswamy S, Herold KC, Herold BC.   +13 more
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1552-1566, June 2026.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source