Results 161 to 170 of about 32,363 (272)

The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency. [PDF]

Cell Rep, 2023
Sperber HS, Raymond KA, Bouzidi MS, Ma T, Valdebenito S, Eugenin EA, Roan NR, Deeks SG, Winning S, Fandrey J, Schwarzer R, Pillai SK.   +11 more
europepmc   +1 more source

Co‐Occurring Risk Factors for Tuberculosis Preventive Treatment Non‐Adherence Among People Living With HIV in Ethiopia: A Latent Class Analysis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective Non‐adherence to tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV) is a critical issue in Ethiopia and other Sub‐Saharan African countries, where both TB and HIV burdens are high. To reduce TPT non‐adherence among PLHIV, it is crucial to identify those at risk and implement targeted interventions. Therefore,
Edao Sinba Etu, Jet Fransen, Biftu Geda, Kemal Ahmed Kuti, Anteneh Fikrie, Mark Spigt   +5 more
wiley   +1 more source

Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats

Transfusion, EarlyView.
Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North, Laurence Corash, Richard J. Benjamin, Nina Mufti   +3 more
wiley   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source

Considerations for the clinical use of teplizumab in stage 2 Type 1 diabetes: A Consensus Statement from the British Society of Paediatric Endocrinology and Diabetes (BSPED) and the Association of British Clinical Diabetologists (ABCD)

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Introduction In 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) approved the use of teplizumab (a monoclonal anti‐CD3 antibody) to delay progression from Stage 2 to Stage 3 Type 1 diabetes in the UK. Methods To address the need for clear guidance on managing patients eligible for teplizumab therapy, the British Society of ...
Renuka P. Dias, M. Loredana Marcovecchio, Ruben H. Willemsen, Fiona Campbell, Ahmad Ashour, Philip Newland‐Jones, Jennifer Cooper, Parth Narendran, Neil P. Wright   +8 more
wiley   +1 more source

HIV Latency and Nanomedicine Strategies for Anti-HIV Treatment and Eradication. [PDF]

Biomedicines, 2023
Andre M, Nair M, Raymond AD.
europepmc   +1 more source

“I'm Not Here to Teach You How to Be Gay:” LGBTQ+ Client Experiences of Othering in Emotionally Focused Couple Therapy

Journal of Marital and Family Therapy, Volume 52, Issue 3, July 2026.
ABSTRACT Despite the increasing emphasis on addressing the intersections of client and therapist identity to improve therapeutic outcomes, therapy clients holding marginalized identities continue to experience othering. Othering is a process that engenders marginalization and inequality based on preconceived group identity, involves the hegemonic ...
Caitlin Edwards, Lekie Dwanyen, Andrea Wittenborn, Robert Allan   +3 more
wiley   +1 more source

Immune checkpoint inhibitors as potential therapy for reverting T-cell exhaustion and reverting HIV latency in people living with HIV. [PDF]

Front Immunol, 2023
Benito JM, Restrepo C, García-Foncillas J, Rallón N.   +3 more
europepmc   +1 more source

Global kidney health: Are we failing the silent pandemic?

Journal of Internal Medicine, Volume 300, Issue 1, Page 26-38, July 2026.
Abstract Chronic kidney disease (CKD), although not infectious, has a sharply rising global incidence, alarming rates of death and disability, and the potential to disrupt health systems and economies. Thus, it demands the urgency and global attention of past pandemics.
Taewon Yi, Daniel V. O'Hara, Adeera Levin   +2 more
wiley   +1 more source

Histone decrotonylation plays a distinct role in HIV latency. [PDF]

Sci Adv
Li X, Li D, Tang Y, Nearing M, Varco-Merth B, Chen H, Smith D, Gianella S, Archin NM, Okoye AA, Dandekar S, Margolis DM, Chirasani VR, Gumpper RH, Jiang G.   +14 more
europepmc   +1 more source