Results 151 to 160 of about 32,488 (258)
Investigations of HIV Latency Through Transcriptomic and Proteomic Profiling [PDF]
, 2016 The human immunodeficiency virus (HIV) has been a global threat for over three decades despite treatments, preventative measures, and public awareness. HIV hides from the immune system by entering a latent state within CD4 T-cells and removal of therapy
White, Cory Haley
core
HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study
Transfusion Medicine, EarlyView.Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira +11 more
wiley +1 more source
Experimental models for HIV latency and molecular tools for reservoir quantification-an update. [PDF]
Clin Microbiol Rev, 2023 Angamuthu D, Vivekanandan S, Hanna LE.
europepmc +1 more source
Tropical Medicine &International Health, EarlyView.ABSTRACT Objective Non‐adherence to tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV) is a critical issue in Ethiopia and other Sub‐Saharan African countries, where both TB and HIV burdens are high. To reduce TPT non‐adherence among PLHIV, it is crucial to identify those at risk and implement targeted interventions. Therefore,
Edao Sinba Etu +5 more
wiley +1 more source
Tropical Medicine &International Health, EarlyView.ABSTRACT Aim This study examines the predictive power of constructs from the health belief model (HBM) and theory of planned behaviour (TPB) in explaining malaria vaccine acceptance in Ghana in the post‐COVID‐19 era, while also assessing the reliability of these constructs within this context.
Michael Sarfo +2 more
wiley +1 more source
HIV-1 Transcription and Latency in the Spotlight
VirusesAt every integrated HIV-1 genome, there is a transcriptional cycle that ultimately shapes proviral fate [...]
openaire +3 more sources
Tropical Medicine &International Health, EarlyView.ABSTRACT Background Asymptomatic tuberculosis (TB) is emerging as a disease state warranting attention because it is presumed infectious, yet affected individuals lack symptoms. The World Health Organization recommends screening for cough, fever, weight loss and night sweats and recently defined asymptomatic TB.
Nunurai Ruswa +4 more
wiley +1 more source
Regulation of HIV-1 latency by basal transcription [PDF]
, 2013 HIV/AIDS is undoubtedly one of mankind’s most pressing health concerns. Currently, there are ~34 million people infected worldwide, with ~3 million new infections and ~2 million deaths every year.
Dahabieh, Matthew Solomon
core
Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats
Transfusion, EarlyView.Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North +3 more
wiley +1 more source
Biomedical Chromatography, Volume 40, Issue 9, September 2026.ABSTRACT Isoniazid (INH) is a key component of tuberculosis treatment regimens but is also associated with hepatotoxicity. This toxicity is mediated in part by its metabolites, but some degrade rapidly in plasma. A rapid freeze/thaw process with a methanol protein precipitation extraction was developed to slow the rapid degradation of acetylisoniazid ...
David Nerguizian +6 more
wiley +1 more source