Results 131 to 140 of about 32,363 (272)
, 2003 Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)-infected patients were used to test the latency model of Pneumocystis infection in the human host.
Denis, CM +4 more
core
Curing HIV: Pharmacologic Approaches to Target HIV-1 Latency
, 2011 HIV-1 infection persists even after years of antiretroviral therapy (ART). Although ART can halt viral replication and thereby reduce viremia to clinically undetectable levels, proviral latency established within the host genome remains largely ...
Margolis, David M. +3 more
core +1 more source
Business Ethics, the Environment &Responsibility, EarlyView.ABSTRACT This paper examines the current state of the art regarding the contribution of Higher Education Institutions (HEIs) to the achievement of the Sustainable Development Goals (SDGs). We conducted a Systematic Literature Review Analysis (SLRA), which integrates a traditional Systematic Literature Review (SLR) with Bibliographic Analysis (BA), on a
Pasquale Latella, Stefania Veltri
wiley +1 more source
HIV-1 latency: From acquaintance to confidant
Journal of Virus EradicationAntiretroviral therapy (ART) has transformed HIV from a fatal disease into manageable circumstance. However, the HIV reservoirs remain a main barrier to complete cure.
Chenbo Yang, Ling Tong, Jing Xue
doaj +1 more source
Chromatin regulation and the histone code in HIV latency
, 2017 The formation of a latent reservoir of Human Immunodeficiency Virus (HIV†) infection hidden from immune clearance remains a significant obstacle to approaches to eradicate HIV infection.
Turner, A.-M.W., Margolis, D.M.
core +1 more source
Hypoxic microenvironment shapes HIV-1 replication and latency
, 2020 : Viral replication is defined by the cellular microenvironment and one key factor is local oxygen tension, where hypoxia inducible factors (HIFs) regulate the cellular response to oxygen.
Ashcroft, Margaret +12 more
core +1 more source
Business Ethics, the Environment &Responsibility, EarlyView.ABSTRACT This study investigates the phenomenon of corporate social responsibility (CSR) decoupling, wherein firms' CSR disclosures diverge from their actual CSR performance, often resulting in misleading portrayals of environmental and social commitments commonly associated with greenwashing.
María Consuelo Pucheta‐Martínez +2 more
wiley +1 more source
BJU International, EarlyView.Background Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–35 years. Management options for men with TGCTs include surgery, radiation and/or chemotherapy, depending on stage. Given TGCTs’ excellent survival, most patients live long enough to experience delayed treatment toxicities, warranting careful consideration of ...
Ahmad Mousa +5 more
wiley +1 more source
Child and Adolescent Mental Health, EarlyView.Background While numerous studies have explored factors contributing to poor mental health, few have examined the combined influence of multiple health and social factors and their cumulative effect. This study specifically aimed to analyze the cumulative effect of multiple health and social factors associated with poor mental well‐being in school‐aged
Marina Robles‐Muñoz +7 more
wiley +1 more source
Bringing Gene Therapy Into Real World Clinical Practice
Haemophilia, EarlyView.ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach +2 more
wiley +1 more source