Results 141 to 150 of about 32,488 (258)
BRD9 functions as an HIV-1 latency regulatory factor [PDF]
A major challenge for HIV type 1 (HIV-1) cure is the presence of viral latent reservoirs. The “Shock & Kill” strategy involves the combined use of latency reversal agents (LRA) and antiretroviral treatment (ART) to reactivate HIV-1 latent reservoirs ...
Zhou, Runhong +14 more
core +1 more source
Viruses, Periodontitis, and Systemic Diseases
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
The Cross and Conflict: How Do Christians Impact Protest Dynamics?
ABSTRACT This study examines the relationship between Christian actors, practices, and sacred sites in US protests and demonstrations, focusing on how political ideology shapes conflict outcomes. Using event‐level data from the Armed Conflict Location & Event Data Project (ACLED), the analysis explores 63,000 protest events from 2020 to 2024 ...
Joel Day
wiley +1 more source
Regulating critical technologies: National security and intellectual property
Abstract In recent years, claims of ‘national security’ have surged internationally to protect various security interests including public health, economic security and cybersecurity. National industrial strategies for building critical technologies challenge the scope of ‘national security’ in international intellectual property (IP) protection ...
Phoebe Li, Atilla Kasap
wiley +1 more source
PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription
HIV-1 infection establishes a reservoir of long-lived cells with integrated proviral DNA that can persist despite antiretroviral therapy (ART). Certain reservoir cells can be reactivated to reinitiate infection.
Luca Love +6 more
doaj +1 more source
ABSTRACT The aims of the present study were to (i) identify profiles of belief in conspiracy theories, and to (ii) test whether the obtained profiles differed in analytical (rational ability, rational engagement, Cognitive Reflection Test) and intuitive thinking (experiential ability, experiential engagement), and science denial (vaccine, climate ...
Peter Karlsson +3 more
wiley +1 more source
Among 346 liver transplant recipients, rural residence conferred a 3.3‐fold higher risk of cryptococcal infection — a novel finding suggesting environmental exposure or healthcare access barriers may drive susceptibility. Triple immunosuppression and longer waitlist duration were additional risk factors, with very early infection carrying the worst ...
Rachel Sigler +11 more
wiley +1 more source
This international cross‐sectional survey of healthcare workers caring for solid organ transplant patients identified knowledge gaps regarding Strongyloides transmission and mortality, particularly among non‐infectious disease providers. Screening strategies varied geographically, with universal screening more common in endemic areas and targeted ...
Jacques Simkins +15 more
wiley +1 more source
ABSTRACT Toxoplasmosis has long been recognized as a serious complication in immunocompromised host, particularly those with advanced HIV/AIDS, hematopoietic stem‐cell transplantation (HSCT), solid‐organ transplant (SOT), and hematological malignancies. The rapid expansion of targeted immunomodulators, including chimeric antigen receptor T‐cell (CAR‐T)
Joy Mouanes‐Abelin +6 more
wiley +1 more source

