Results 71 to 80 of about 299,964 (312)

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

HIV Replication Under High-Level Cabotegravir Is Associated with the Appearance of 3′-PPT Mutations, Circular DNA Transcription and Recombination

Viruses
The HIV integrase inhibitor, dolutegravir (DTG), in the absence of eliciting integrase (int) resistance, has been reported to select mutations in the virus 3′-polypurine tract (3′-PPT) adjacent to the 3′-LTR U3.
Xierong Wei, Jonathan T. Lipscomb, Ariana Santos Tino, Mian-er Cong, Susan Ruone, Meghan L. Bentz, Mili Sheth, Gerardo Garcia-Lerma, Jeffrey A. Johnson   +8 more
doaj   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

HIV prevention and care outcomes [PDF]

Publication date from document propertieslcdc-hiv-prevention-and-care-outcomes ...

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Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

HIV prevention progress in the United States [PDF]

"The Centers for Disease Control and Prevention (CDC) works with other federal agencies, state and local health departments, national organizations, community-based organizations, the private sector, and advocates to reduce the spread of HIV in the U.S ...

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HIV prevention in Mexican schools: prospective randomised evaluation of intervention. [PDF]

, 2006
OBJECTIVE: To assess effects on condom use and other sexual behaviour of an HIV prevention programme at school that promotes the use of condoms with and without emergency contraception. DESIGN: Cluster randomised controlled trial. SETTING: 40 public high
Walker, Dilys, Dilys Walker, Bertozzi, Stefano M, Pilar Torres, Juan Pablo Gutierrez, Gutierrez, Juan Pablo, Torres, Pilar, Stefano M Bertozzi   +7 more
core   +1 more source

A population-based survey pooled analysis of women engaged in commercial sex in the HIV care cascade in sub-Saharan Africa, 2015–2017

Discover Public Health
Introduction Women who engage in commercial sex (WCS) have a higher prevalence of HIV in sub-Saharan Africa than other women of reproductive age. We aimed to describe the burden of HIV, testing, treatment, and viral load suppression (VLS) coverage among ...
Forrest Larson, Gordon Le, Italia V. Rolle, Madeline Sands, Faith Ussery, Abraham Ater, Abu Abdul-Quader, Gary Sardon, Neena M. Philip, Felix Ndagije, Gerald Mwima, George Mgomella, Fred M. Asiimwe, Tendayi Mharadze, Nzali G. Kancheya, Fatima Glyn Zulu, Mandzisi Mkhontfo   +16 more
doaj   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

National HIV prevention progress report, 2013 [PDF]

The Centers for Disease Control and Prevention (CDC) is the nation\u2019s health protection agency. As part of the CDC\u2019s National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, the Division of HIV/AIDS Prevention (DHAP) promotes ...

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