Results 161 to 170 of about 118,257 (252)

Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, London, UK [PDF]

, 2013
Alderton, W K, Anderson, Rosaleen, Collingwood, S P, Pryde, D C   +3 more
core   +1 more source

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley   +1 more source

Antiretroviral effect of 4-thio-uridylate against human immunodeficiency virus type 1 [PDF]

, 2012
Albert J., Barbouche R., Beck Z., Berger E. A., Clapham P., Cox S., Doms R. W., Einfeld D., Fenouillet E., Horváth A., Horváth A., Joseph Ongrádi, Juhász E., Kanizsai S., Kanizsai Sz., Kemény B., Kilby J. M., Károly Nagy, Leonard C., Markovic I., Matthias L. J., Nagy K., Nagy K., Nagy K., Nisole S., Ou W., Ryser H. J., Szatmari I., Szilvia Kanizsai, Tarkanyi I., Tõkés S., Wittinghoff E., Ágoston Ghidán   +32 more
core   +1 more source

Live-Cell Raman Imaging Elucidates Intracellular Distribution of Macrocyclic Peptides Designed as HIV Protease Inhibitors. [PDF]

Chem Biomed Imaging
Nawa Y, Miyano T, Bando K, Mitsuki S, Hayashi K, Tanaka Y, Ueda H, Fujita S, Fujita K.   +8 more
europepmc   +1 more source

Improving Treatment Outcome for Children with HIV [PDF]

, 2011
Calmy, Alexandra L, Ford, Nathan
core   +2 more sources

Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B's antifungal efficacy in cryptococcosis. [PDF]

PLoS One
Alkashef NM, Seleem MN.
europepmc   +1 more source

HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer. [PDF]

Br J Cancer
Besse A, Sedlarikova L, Buechler L, Kraus M, Yang CH, Strakova N, Soucek K, Navratil J, Svoboda M, Welm AL, Joerger M, Driessen C, Besse L.   +12 more
europepmc   +1 more source

Enhanced antifungal activity of posaconazole against Candida auris by HIV protease inhibitors, atazanavir and saquinavir. [PDF]

Sci Rep
Elgammal Y, Salama EA, Seleem MN.
europepmc   +1 more source

Applications of Click Chemistry in the Development of HIV Protease Inhibitors. [PDF]

Int J Med Chem, 2018
Mudgal MM, Birudukota N, Doke MA.
europepmc   +1 more source

Counteracting Akt Activation by HIV Protease Inhibitors in Monocytes/Macrophages. [PDF]

Viruses, 2018
Pasquereau S, Kumar A, Abbas W, Herbein G.   +3 more
europepmc   +1 more source