Results 161 to 170 of about 58,529 (279)

Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B's antifungal efficacy in cryptococcosis. [PDF]

PLoS One
Alkashef NM, Seleem MN.
europepmc   +1 more source

Hepatitis C virus-associated hepatitis following treatment of HIV-infected patients with HIV protease inhibitors

, 1998
Mina John, James Flexman, Martyn A. French   +2 more
openalex   +1 more source

Inhibition of OATP1B1/3 Rather Than UGT1A1 May Be the Major Cause of the Bilirubin Elevation After Atazanavir Administration

Clinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 497-509, August 2025.
Atazanavir has been reported to increase total serum bilirubin level up to ninefold. It is widely believed that the observed total bilirubin elevation is primarily due to UGT1A1 inhibition. However, UGT enzymes are well‐known as a low‐affinity and high‐capacity system, and the observed drug–drug interaction mediated by UGTs is usually less than twofold.
Jin Dong, Pradeep Sharma, Rasha Emara, Derek Cheung, Weifeng Tang, Diansong Zhou, David W. Boulton, Mats Någård, Miki S. Park   +8 more
wiley   +1 more source

HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer. [PDF]

Br J Cancer
Besse A, Sedlarikova L, Buechler L, Kraus M, Yang CH, Strakova N, Soucek K, Navratil J, Svoboda M, Welm AL, Joerger M, Driessen C, Besse L.   +12 more
europepmc   +1 more source

Angiotensin II Type 1 Receptor Blocker Usage Prevents Oxidative Stress and Muscle Dysfunction in HIV

Fundamental &Clinical Pharmacology, Volume 39, Issue 4, August 2025.
ABSTRACT Background We aimed to elucidate the role of Angiotensin II type 1 receptor (AT1R) blocker usage in muscle wasting and dysfunction related to HIV. Research Design and Methods Appendicular skeletal muscle mass, higher and lower limb strength, and physical fitness were determined in people living with HIV (PWH) using AT1R blockers users (n = 33),
Rafael Deminice, Paola Sanches Cella, Ana Lúcia Borsari, Camila S. Padilha, Vitor Hugo Fernando de Oliveira   +4 more
wiley   +1 more source

Enhanced antifungal activity of posaconazole against Candida auris by HIV protease inhibitors, atazanavir and saquinavir. [PDF]

Sci Rep
Elgammal Y, Salama EA, Seleem MN.
europepmc   +1 more source

Applications of Click Chemistry in the Development of HIV Protease Inhibitors. [PDF]

Int J Med Chem, 2018
Mudgal MM, Birudukota N, Doke MA.
europepmc   +1 more source

The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir

, 1998
Dale J. Kempf, Richard A. Rode, Yi Xu, Eugene Sun, Margo Heath‐Chiozzi, Joaquin Valdes, Anthony J. Japour, Sven Danner, Charles A. Boucher, Akhteruzzaman Molla, John M. Leonard   +10 more
openalex   +1 more source

Effect of Protease Inhibitors Combined with Standard Antiretroviral Therapy on Linear Growth and Weight Gain in HIV-1-Infected Children [PDF]

, 1999
Daina Dreimane, Karin Nielsen, Yvonne J. Bryson, Mitchell E. Geffner   +3 more
openalex   +1 more source

Increased CD8dim and Decreased CD8bright T Cells as Immunological Signature for Multibacilary Leprosy Patients

Immunology, Volume 175, Issue 4, Page 444-452, August 2025.
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, manifests in a spectrum of clinical forms and severity. This study investigated the percentage of CD8+ T cells and their subpopulations (CD8bright and CD8dim T cells) in leprosy patients stratified by clinical forms, bacterial load, and age.
Yuri Scheidegger de Castro, Letícia Silva Nascimento, Juliana Azevedo da Silva, Rebeka da Conceição Souza, Gabriel Nogueira Araújo, Sandra Chalhub de Oliveira, Edilbert Pellegrini Nahn Junior, Alba Lucínia Peixoto‐Rangel   +7 more
wiley   +1 more source