Results 61 to 70 of about 36,601 (210)

The Impact of Domestic Public Health Spending on Health Outcomes in Sub‐Saharan Africa: Evidence From Disability‐Adjusted Life Years

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Sub‐Saharan Africa (SSA) continues to experience a high and uneven disease burden, mainly from HIV/AIDS, tuberculosis, and malaria. As external funding declines, the strategic allocation of domestic public health spending (DPHS) becomes crucial.
Wa Ntita Serge Kabongo, Josue Mbonigaba
wiley   +1 more source

Clearance of high‐risk human papillomavirus in patients with cervical intraepithelial neoplasia 2–3 after the loop electrosurgical excision procedure with negative resection margins

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aims to evaluate the longitudinal clearance rates of high‐risk human papillomavirus (hr‐HPV) and the incidence of clinical recurrence (defined by abnormal cytology or histologically confirmed cervical intraepithelial neoplasia; CIN) at 6 and 18 months post‐loop electrosurgical excision procedure (LEEP), characterizing the ...
Praew Sittichivapak, Pattama Chaopotong
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites

open access: yesHIV/AIDS - Research and Palliative Care, 2010
Even though the treatment of human immunodeficiency virus (HIV)-infected individuals with highly active antiretroviral therapy (HAART) provides a complete control of plasma viremia to below detectable levels (
Nitin K, Saksena   +5 more
openaire   +3 more sources

Targeting the Latent Reservoir for HIV-1 [PDF]

open access: yesImmunity, 2018
Antiretroviral therapy can effectively block HIV-1 replication and prevent or reverse immunodeficiency in HIV-1-infected individuals. However, viral replication resumes within weeks of treatment interruption. The major barrier to a cure is a small pool of resting memory CD4+ T cells that harbor latent HIV-1 proviruses.
Srona, Sengupta, Robert F, Siliciano
openaire   +2 more sources

Linking gut microbiome to HIV-1 reservoir size in people living with HIV

open access: yesGut Pathogens
The gut microbiome is altered during HIV-1 infection and contributes to immune dysfunction and inflammation in people living with HIV (PLWH), these changes may persist despite effective antiretroviral therapy (ART).
Oscar Kieri   +7 more
doaj   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

open access: yesResponsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan   +8 more
wiley   +1 more source

Emerging strategies to deplete the HIV reservoir

open access: yesCurrent Opinion in Infectious Diseases, 2014
This review highlights recent studies undertaken to further advance the search for successful approaches to eradicate HIV infection.
Nancie M, Archin, David M, Margolis
openaire   +3 more sources

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