Results 61 to 70 of about 63,834 (200)
Small Methods, EarlyView.This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang +13 more
wiley +1 more source
Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19
Aging Cell, EarlyView.(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura +40 more
wiley +1 more source
EFFICACY OF COMBINED THERAPY IN CHILDREN WITH HIV INFECTION
Педиатрическая фармакология, 2010 To achieve a sustainable virus replication suppression, positive dynamics in clinical and immunologic metrics of children with HIV infection, it is necessary to use the most efficient, safe and convenient patterns of highly active antiretroviral therapy.
E.N. Simovan'yan, V.B. Denisenko
doaj +2 more sources
Opportunities and Challenges of Population Pharmacogenomics
Annals of Human Genetics, EarlyView.ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou +3 more
wiley +1 more source
Virology JournalThe human T-lymphotropic virus type 1 (HTLV-1) infects millions of people globally and is endemic to various resource-limited regions. Infections persist for life and are associated with increased susceptibility to opportunistic infections and severe ...
Nicolas Tardiota +4 more
doaj +1 more source
Prevalence of genotypic HIV-1 drug resistance in Thailand, 2002
Annals of Clinical Microbiology and Antimicrobials, 2003 Background The prices of reverse transcriptase (RT) inhibitors in Thailand have been reduced since December 1, 2001. It is expected that reduction in the price of these inhibitors may influence the drug resistance mutation pattern of HIV-1 among infected
Watitpun Chotip +3 more
doaj +1 more source
HIV Medicine, EarlyView.Abstract Background Traditionally, ≥95% adherence was recommended for viral suppression (VS). Newer antiretroviral therapy (ART) is now being increasingly prescribed and may be more forgiving of lower adherence. The lifelong nature of ART presents adherence challenges, particularly for women living with HIV. We aimed to describe ART use and examine the
Maysaloun Mokaddam +125 more
wiley +1 more source
The role of the glycosyl moiety of myricetin derivatives in anti-HIV-1 activity in vitro
AIDS Research and Therapy, 2017 Background Plant extracts are sources of valuable compounds with biological activity, especially for the anti-proliferative activity against pathogens or tumor cells.
Joseph T. Ortega +5 more
doaj +1 more source
HIV Medicine, EarlyView.Abstract Background Limited data exist describing metabolic syndrome (MetS) and Pathobiological Determinants of Atherosclerosis in Youth (PDAY) coronary arteries (CA) and abdominal aorta (AA) risk scores in youth with HIV in sub‐Saharan Africa.
Sahera Dirajlal‐Fargo +14 more
wiley +1 more source
HIV Medicine, EarlyView.Abstract Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine (CAB + RPV) in virologically suppressed people with HIV.
Ishfaq Rashid +12 more
wiley +1 more source