Results 21 to 30 of about 4,770 (153)
Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival [PDF]
, 2016 The Piwi-piRNA pathway is important for germ cell maintenance, genome integrity, DNA methylation and retrotransposon control and thus may be involved in cancer development.
Amos, Christopher I. +10 more
core +2 more sources
Reconstructing prehistoric demography: What role for extant hunter‐gatherers?
Evolutionary Anthropology: Issues, News, and Reviews, Volume 29, Issue 6, Page 332-345, November/December 2020., 2020 Abstract Demography is central to biological, behavioral, and cultural evolution. Knowledge of the demography of prehistoric populations of both Homo sapiens and earlier members of the genus Homo is, therefore, key to the study of human evolution.
Abigail E. Page, Jennifer C. French
wiley +1 more source
Angewandte Chemie, Volume 137, Issue 46, November 10, 2025.Accidentally reversing the lanthanide‐binding sequences of lanmodulin‐inspired short peptides lead to the serendipitous discovery of a set of peptides with a one order of magnitude higher lanthanide‐binding affinity than the uncapped peptides synthesised in the correct direction.
Sophie M. Gutenthaler‐Tietze +5 more
wiley +2 more sources
Maximizing sum rate and minimizing MSE on multiuser downlink: Optimality, fast algorithms and equivalence via max-min SIR [PDF]
, 2009 Maximizing the minimum weighted SIR, minimizing the weighted sum MSE and maximizing the weighted sum rate in a multiuser downlink system are three important performance objectives in joint transceiver and power optimization, where all the users have a ...
Chiang, Mung, Srikant, R., Tan, Chee Wei
core +1 more source
Genetic disorders and male infertility
Reproductive Medicine and Biology, Volume 19, Issue 4, Page 314-322, October 2020., 2020 Abstract Background At present, one out of six couples is infertile, and in 50% of cases, infertility is attributed to male infertility factors. Genetic abnormalities are found in 10%‐20% of patients showing severe spermatogenesis disorders, including non‐obstructive azoospermia.
Shinnosuke Kuroda +6 more
wiley +1 more source
Cancer Medicine, Volume 9, Issue 5, Page 1937-1950, March 2020., 2020 Our study evaluated the cumulative evidence of significant associations between SNPs in miRNA or biosynthesis genes and lung cancer (LC) risk by combining Venice Criteria and false‐positive report probability test. Two variants with four associations were rated as demonstrating strong evidence with risk of LC, three associations were moderate, and ...
Guanchu Liu +5 more
wiley +1 more source
PIWI expression and function in cancer
Frontiers in Genetics, 2012 PIWI proteins, a subclade of the Argonaute family proteins, are expressed predominantly in the germline and bind to PIWI-interacting RNAs (piRNAs), which are 25-31 nucleotides in length. The PIWI/piRNA pathway plays critical roles in germline development
Ryusuke eSuzuki +2 more
doaj +1 more source
Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic Cells
Cell Reports, 2012 Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have been shown to differentiate into primordial germ cells (PGCs) but not into spermatogonia, haploid spermatocytes, or spermatids.
Charles A. Easley, IV +10 more
doaj +1 more source
Suppression of Hiwi inhibits the growth and epithelial-mesenchymal transition of cervical cancer cells. [PDF]
Oncol Lett, 2018 Cervical cancer is a common gynecological malignancy. Hiwi exhibits a high level of expression in cervical cancer cells. However, the effects of Hiwi expression in cervical cancer cells remain unresolved. In the present study, the effects of Hiwi downregulation on the growth and epithelial-mesenchymal transition of cervical cancer cells were ...
Pei G, Li B, Ma A.
europepmc +4 more sources
On the Capacity Region of Multi-Antenna Gaussian Broadcast Channels with Estimation Error [PDF]
, 2006 In this paper we consider the effect of channel estimation error on the capacity region of MIMO Gaussian broadcast channels. It is assumed that the receivers and the transmitter have (the same) estimates of the channel coefficients (i.e., the feedback ...
Dana, Amir F. +2 more
core +1 more source