Results 71 to 80 of about 223,968 (292)
Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication
Annals of the Rheumatic Diseases, 2018 Objective Salmonella enterica infections can lead to Reactive Arthritis (ReA), which can exhibit an association with human leucocyte antigen (HLA)-B*27:05, a molecule prone to misfolding and initiation of the unfolded protein response (UPR).
A. Antoniou +12 more
semanticscholar +1 more source
Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis
Arthritis &Rheumatology, EarlyView.Objective Patients with juvenile idiopathic arthritis (JIA) frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in patients with JIA remains elusive.
Viola Pitkänen +13 more
wiley +1 more source
Clinical and MRI responses to etanercept in early non-radiographic axial spondyloarthritis : 48-week results from the EMBARK study [PDF]
, 2015 Objective: To evaluate the efficacy and safety of etanercept (ETN) after 48 weeks in patients with early active non-radiographic axial spondyloarthritis (nr-axSpA).
Bonin, Randi +15 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Fecal microbiota transplantation (FMT) holds promises as a beneficial supplement to methotrexate in patients with psoriatic arthritis (PsA). We therefore investigated how gut bacterial signatures in patients and donor strain engraftment were associated with long‐term response to FMT.
Panpan Qin +7 more
wiley +1 more source
Kurdistan Journal of Applied ResearchRheumatoid arthritis (RA) is a predominant inflammatory arthritis in human. The function of HLA-B27 gene in other types of arthritis has been studied, however, its function in RA is unclear. This study investigated the relative expression of HLA-B27 gene
Karzan Ghafur Khidhir +2 more
doaj +1 more source
Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27
Frontiers in Immunology, 2022 Ankylosing spondylitis (AS) belongs to a group of diseases, called spondyloarthropathies (SpA), that are strongly associated with the genetic marker HLA-B27. AS is characterized by inflammation of joints and primarily affects the spine. Over 160 subtypes
Amit Kumar Thakur +1 more
doaj +1 more source
Polimorfismo do alelo HLA-B27 no desenvolvimento das espondilartropatias [PDF]
, 2005 A associação da molécula HLA-B27 com a espondilite anquilosante (AS) e outras espondilartropatias (SpA), permanece como uma das mais fortes verificada entre moléculas HLA e doenças humanas.
Brehm, António +8 more
core
The performance of different classification criteria sets for spondyloarthritis in the worldwide ASAS-COMOSPA study [PDF]
, 2017 Background: In this study, we sought to compare the performance of spondyloarthritis (SpA) classification criteria sets in an international SpA cohort with patients included from five continents around the world.
Bakker, Pauline +7 more
core +2 more sources
Arthritis &Rheumatology, EarlyView.Objective This study aims to investigate the impact of nonsteroidal anti‐inflammatory drug (NSAID) intake on radiographic spinal progression in axial spondyloarthritis (axSpA), considering different NSAID types (COX‐2 inhibitors [COX2i] and nonselective NSAIDs [ns‐NSAIDs]) and disease subgroups (radiographic [r‐axSpA] and nonradiographic [nr‐axSpA ...
Murat Torgutalp +8 more
wiley +1 more source
Human Leukocyte Antigen B27‐Negative Axial Spondyloarthritis: What Do We Know?
ACR Open Rheumatology, 2023 Axial spondyloarthritis (axSpA) is a chronic, immune‐mediated disease characterized by inflammatory axial skeleton involvement and extra‐musculoskeletal manifestations.
Atul Deodhar, Tejpal Gill, Marina Magrey
doaj +1 more source