Results 81 to 90 of about 141,660 (219)
New aspects of spondyloarthritis pathogenesis. Part I. Genetic factors and role of HLA-B27 molecules
, 2014 Recent data verify understanding of spondyloarthritis (SpA) pathogenesis by showing that there is the overlap between traditionally classified subtypes in terms of genetic background (HLA-B27 alleles, variants of IL-23R, ERAP1 and ERAP2 genes), which is ...
Ewa Kontny
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Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.ABSTRACT Background Psoriatic arthritis (PsA) is a chronic inflammatory disease with complex pathophysiology. Despite advancements in biologic and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs), treatment responses remain suboptimal for many patients.
Mengduan Pang +3 more
wiley +1 more source
Hematological Inflammation Indices Are Associated With Active Uveitis in Ankylosing Spondylitis
Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.Hematological inflammation indices reflect the systemic inflammatory burden in ankylosing spondylitis. Patients with active uveitis exhibit a distinct pro‐inflammatory profile characterised by increased NLR, PLR, SII, SIRI, and AISI, along with decreased HALP and CALLY scores.
Mesude Seda Aydoğdu, Zarife Ekici Gök
wiley +1 more source
Pediatric Systemic Lupus Erythematosus Complicated by Acute EBV and CMV Co‐infection
Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.This case report describes a 10‐year‐old girl with new‐onset pediatric SLE who presented with malar rash, fever, and arthritis following sun exposure, alongside serological evidence of acute Epstein–Barr virus (EBV) and cytomegalovirus (CMV) co‐infection.
Anning Chen +7 more
wiley +1 more source
The role of HLA-B27 in spondyloarthritis
Immunogenetics, 1999 The human major histocompatibility complex (MHC) class I allele HLA-B27 bears a striking association with the spondylolarthritic group of inflammatory arthritides, yet despite extensive studies its role in the disease process remains obscure. As an MHC class I protein, the primary function of HLA-B27 is to complex with beta(2)-microglobulin forming a ...
Allen, R, Bowness, P, McMichael, A
openaire +3 more sources
BMC Musculoskeletal Disorders, 2017 Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population.
Nelly Raymond Ziade
doaj +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 241-259, September 2026.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
, 2019 Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative Turkish cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).
Fernur Çapa (6556490) +29 more
core +1 more source
Disease‐Intrinsic Organising Pneumonia During Biomarker‐Confirmed Ulcerative Colitis Remission
Respirology Case Reports, Volume 14, Issue 9, September 2026.Organising pneumonia (OP) can occur as a disease‐intrinsic extraintestinal manifestation of ulcerative colitis (UC) during biochemical remission. Drug‐induced aetiology must be systematically excluded before attributing OP to UC. Cryobiopsy‐based ILD diagnoses require expert pathology review when treatment decisions are consequential, as the ...
Rahaf A. Jereisat +2 more
wiley +1 more source
, 2019 Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative combined cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).
Fernur Çapa (6556490) +29 more
core +1 more source