Results 81 to 90 of about 116,043 (221)
Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V. +5 more
core +1 more source
ABSTRACT Morphea is a localized autoimmune fibrosing disorder that may paradoxically develop during anti‐TNFα agents in ankylosing spondylitis (AS). We report a second case of morphea associated with long‐term golimumab use in a patient with AS, presenting with indurated plaques and confirmed histopathologically.
Faten Hilwanjee +3 more
wiley +1 more source
The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. [PDF]
Chlamydia-specific cytotoxic T lymphocytes are able to control model infections but may be implicated in disease pathogenesis. HLA-A2 peptide tetramers to Chlamydia trachomatis major outer membrane protein 258-266 (MOMP258-266) and MOMP260-268 were used ...
Nkoyo Faal +19 more
core +1 more source
Aim: This study aimed to evaluate the frequency of human leukocyte antigen (HLA)-B27 positivity and its clinical correlations in Turkish patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated ...
Dilara BULUT GÖKTEN +3 more
doaj +1 more source
Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population.
Nelly Raymond Ziade
doaj +1 more source
Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative Turkish cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).
Fernur Çapa (6556490) +29 more
core +1 more source
Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative combined cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).
Fernur Çapa (6556490) +29 more
core +1 more source
OBJETIVO: analisar o padrão de doença de pacientes brasileiros com espondiloartropatias (EAP). PACIENTES E MÉTODOS: foram avaliados 156 pacientes por meio de análise descritiva e análise de associação uni e multivariada entre a distribuição das ...
Carlos Alexandre de Souza Bomtempo +3 more
doaj +1 more source
La asociación del HLA-B27 y las Espondiloartritis, ha hecho evidente que la tipificación del HLA-B27 sea considerada como un apoyo en el diagnóstico de estas enfermedades.
Briceño, I +21 more
core +1 more source
The role of HLA-B27 in spondyloarthritis
The human major histocompatibility complex (MHC) class I allele HLA-B27 bears a striking association with the spondylolarthritic group of inflammatory arthritides, yet despite extensive studies its role in the disease process remains obscure. As an MHC class I protein, the primary function of HLA-B27 is to complex with beta(2)-microglobulin forming a ...
Allen, R, Bowness, P, McMichael, A
openaire +3 more sources

