Results 81 to 90 of about 116,043 (221)

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

open access: yes, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V.   +5 more
core   +1 more source

Morphea Induced by Golimumab in a Patient With Ankylosing Spondylitis: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Morphea is a localized autoimmune fibrosing disorder that may paradoxically develop during anti‐TNFα agents in ankylosing spondylitis (AS). We report a second case of morphea associated with long‐term golimumab use in a patient with AS, presenting with indurated plaques and confirmed histopathologically.
Faten Hilwanjee   +3 more
wiley   +1 more source

The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. [PDF]

open access: yes, 2006
Chlamydia-specific cytotoxic T lymphocytes are able to control model infections but may be implicated in disease pathogenesis. HLA-A2 peptide tetramers to Chlamydia trachomatis major outer membrane protein 258-266 (MOMP258-266) and MOMP260-268 were used ...
Nkoyo Faal   +19 more
core   +1 more source

HLA-B27 Frequency and Clinical Correlates in Turkish Patients with Various Subtypes of Spondyloarthritis: A Single-Center Cohort Study

open access: yesNamık Kemal Tıp Dergisi
Aim: This study aimed to evaluate the frequency of human leukocyte antigen (HLA)-B27 positivity and its clinical correlations in Turkish patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated ...
Dilara BULUT GÖKTEN   +3 more
doaj   +1 more source

HLA B27 antigen in Middle Eastern and Arab countries: systematic review of the strength of association with axial spondyloarthritis and methodological gaps

open access: yesBMC Musculoskeletal Disorders, 2017
Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population.
Nelly Raymond Ziade
doaj   +1 more source

Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative Turkish cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).

open access: yes, 2019
Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative Turkish cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).
Fernur Çapa (6556490)   +29 more
core   +1 more source

Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative combined cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).

open access: yes, 2019
Genotype counts and (%) of rs61752717 in HLA-B27-positive and HLA-B27-negative combined cohorts (including four HLA-B27-negative subjects with co-existent AS and FMF, three homozygous for rs61752717 ‘C’ allele, one homozygote for rs61752717 ‘T’ allele).
Fernur Çapa (6556490)   +29 more
core   +1 more source

Avaliação clínica, laboratorial e radiográfica de brasileiros com espondiloartropatias Clinical, laboratorial and radiographic evaluation in Brazilians with spondyloarthropaties

open access: yesRevista Brasileira de Reumatologia, 2006
OBJETIVO: analisar o padrão de doença de pacientes brasileiros com espondiloartropatias (EAP). PACIENTES E MÉTODOS: foram avaliados 156 pacientes por meio de análise descritiva e análise de associação uni e multivariada entre a distribuição das ...
Carlos Alexandre de Souza Bomtempo   +3 more
doaj   +1 more source

Métodos para la identificación del antígeno de histocompatibilidad HLA-B27: comparación de cuatro protocolos técnicos

open access: yes, 2015
La asociación del HLA-B27 y las Espondiloartritis, ha hecho evidente que la tipificación del HLA-B27 sea considerada como un apoyo en el diagnóstico de estas enfermedades.
Briceño, I   +21 more
core   +1 more source

The role of HLA-B27 in spondyloarthritis

open access: yesImmunogenetics, 1999
The human major histocompatibility complex (MHC) class I allele HLA-B27 bears a striking association with the spondylolarthritic group of inflammatory arthritides, yet despite extensive studies its role in the disease process remains obscure. As an MHC class I protein, the primary function of HLA-B27 is to complex with beta(2)-microglobulin forming a ...
Allen, R, Bowness, P, McMichael, A
openaire   +3 more sources

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