Results 61 to 70 of about 116,043 (221)

Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27

Frontiers in Immunology, 2022
Ankylosing spondylitis (AS) belongs to a group of diseases, called spondyloarthropathies (SpA), that are strongly associated with the genetic marker HLA-B27. AS is characterized by inflammation of joints and primarily affects the spine. Over 160 subtypes
Amit Kumar Thakur, Manni Luthra-Guptasarma   +1 more
doaj   +1 more source

The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study. [PDF]

J Neuroinflammation
BACKGROUND The human gut microbiome (GM) is involved in inflammation and immune response regulation. Dysbiosis, an imbalance in this ecosystem, facilitates pathogenic invasion, disrupts immune equilibrium, and potentially triggers diseases including ...
Morandi SC, Herzog EL, Munk M, Kreuzer M, Largiadèr CR, Wolf S, Zinkernagel M, Zysset-Burri DC.   +7 more
europepmc   +2 more sources

Inflammatory Pseudotumor After Total Hip Arthroplasty‐An Increasingly Recognized Complication

Orthopaedic Surgery, EarlyView.
This review systematically elucidates the clinical characteristics and management of inflammatory pseudotumor (IP) across different bearing surfaces, addressing a topic of increasing concern and providing a novel perspective. It synthesizes the five primary risk factors associated with IP, offering clinicians critical reference points.
Steve T. L. Pambayi, Zhi Zhao, Hongjun Peng, Ruihao Xia, Xishan Zhu, Wangdui Suolang, Gang Wang, Xiaoou Li, Yi Zeng   +8 more
wiley   +1 more source

The MHC Class I Heavy Chain Structurally Conserved Cysteines 101 and 164 Participate in HLA-B27 Dimer Formation

, 2012
The human leukocyte antigen (HLA)-B27 is strongly associated with a group of inflammatory arthritic disorders known as the spondyloarthropathies (SpAs).
Guiliano, D.B., Powis, S.J., Campbell, E.C., Fussell, H., Burn, G., Lenart, I., Antoniou, A.N., Morley, K.D.   +7 more
core   +1 more source

Epidemiologic and ophthalmologic characteristics of patients with HLA-B27-associated uveitis.

, 2020
Epidemiologic and ophthalmologic characteristics of patients with HLA-B27-associated uveitis.
Pierre Pradat (816487), Roland Chapurlat (283094), Nabil Bouzid (8648571), Laurent Kodjikian (5488115), Yvan Jamilloux (436733), Audrey De Parisot (8648574), Pascal Sève (4449340)   +6 more
core   +1 more source

CHOP-mediated IL-23 overexpression does not drive colitis in experimental spondyloarthritis

Scientific Reports
HLA-B27 is a major risk factor for spondyloarthritis (SpA), yet the underlying mechanisms remain unclear. HLA-B27 misfolding-induced IL-23, which is mediated by endoplasmic reticulum (ER) stress has been hypothesized to drive SpA pathogenesis. Expression
Fatemeh Navid, Tejpal Gill, Lilah Fones, Jules D. Allbritton-King, Kelly Zhou, Isabel Shen, Jinny Van Doorn, Francesca LiCausi, Antony Cougnoux, Davide Randazzo, Stephen R. Brooks, Robert A. Colbert   +11 more
doaj   +1 more source

Clinical Images: Skeletal fluorosis presenting with diffuse periostitis and polyarticular synovitis

Arthritis &Rheumatology, EarlyView.
Mitali Sen
wiley   +1 more source

Atypical Case of Takayasu Aortitis Presenting as Embolic Stroke With Concomitant Massive Thoracic Artery Aneurysm

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Multifocal aortic aneurysmal dilatation as evidenced by CT Angiography chest‐abdomen‐pelvis of the ascending aorta (A), aortic arch (B), and suprarenal abdominal aorta (C), measuring 6.0 × 6.0, 4.5 × 4.5, and 4.1 × 3.7 cm, respectively. ABSTRACT We describe the case of a 44‐year‐old female with a history significant for only hypertension who presented ...
J. Curran Henson, Jordan H. Myers, Macy Cummins, Keyur Vyas, Michael Lowry   +4 more
wiley   +1 more source

Bilateral Avascular Necrosis of the Femoral Heads in Ankylosing Spondylitis Requiring Staged Total Hip Arthroplasty: A Case Report of Diagnostic and Therapeutic Challenges

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Ankylosing spondylitis (AS) is a chronic immune‐mediated inflammatory arthropathy primarily affecting the axial skeleton but may involve peripheral joints, particularly the hips. Avascular necrosis (AVN) of the femoral head represents a severe, underrecognized complication whose pathogenesis in AS is multifactorial—encompassing disease ...
Syeda Simrah Shah, Muhammad Ahsan, Tehreem Farooq, Mirza Daniyal Baig, Mirza Mohammad Ali Baig, Mohammed Hammad Jaber Amin   +5 more
wiley   +1 more source

Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population

Journal of Ophthalmology, 2020
Purpose. To report on patients who needed hospitalization due to acute anterior uveitis (AAU) and within this group to compare clinical features and outcomes of treatment of HLA-B27+ and HLA-B27− AAU in the population of Slovenian patients.
Katarina Vergot, Sasa Pockar, Lan Umek, Natasa Vidovic Valentincic   +3 more
doaj   +1 more source