Original paper Prevalence of HLA-B27 antigen in patients with juvenile idiopathic arthritis [PDF]
Introduction: Human leukocyte antigen B27 (HLA-B27) is considered as a risk factor for development of juvenile idiopathic arthritis (JIA). The aim of this study was to analyse the prevalence of HLA-B27 antigen in JIA categories and its influence on ...
Zbigniew Żuber +3 more
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Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić +5 more
doaj +2 more sources
HLA B27 antigen in Middle Eastern and Arab countries: systematic review of the strength of association with axial spondyloarthritis and methodological gaps [PDF]
Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population.
Nelly Raymond Ziade
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Does HLA-B27 Status Influence Ixekizumab Efficacy in Axial Spondyloarthritis? Results From the COAST-V, COAST-W, and COAST-X Trials [PDF]
Introduction The human leukocyte antigen (HLA)-B27 is associated with axial spondyloarthritis (axSpA) and is a predictor of response to tumor necrosis factor inhibitors. However, limited data are available on HLA-B27 and interleukin-17 inhibitors.
John D. Reveille +11 more
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Mimicry of human histocompatibility HLA-B27 antigens by Klebsiella pneumoniae [PDF]
Anti-HLA-B27 monoclonal antibody M2, which was relatively specific for human histocompatibility antigen HLA-B27, was used to test several bacteria, some of which could potentially induce chronic arthritis in HLA-B27-positive individuals. Using the Western blot procedure, we observed positive reactions with 80,000- and 60,000-dalton antigens with one ...
M, Ogasawara, D H, Kono, D T, Yu
openaire +3 more sources
HLA-B27 (antigen) in retroperitoneal fibrosis in a family
Idiopathic retroperitoneal fibrosis is a rare disease of undetermined aetiology. It is important to distinguish this entity from retroperitoneal fibrosis secondary to malignancy or specific inflammatory disease.
Mohammad Yazdani, Afshin Shadmehr
doaj +2 more sources
Objective: The aim of this study was to research the frequency of Human Leukocyte Antigen (HLA)-B27 antigen positivity and relationship between HLA-B27 positivity and other autoantibodies and between HLA-B27 positivity and ...
Gülseren Demir Karakılıç +2 more
doaj +2 more sources
Flow cytometric HLA‐B27 screening: Cross‐reactivity patterns of commercially available anti–HLA‐B27 monoclonal antibodies with other HLA‐B antigens [PDF]
AbstractBackgroundSome 50 clinical laboratories in the Benelux perform flow cytometric HLA‐B27 screening and participate in the Benelux external quality assessment scheme operational since 1995. Results from this scheme indicate that cross‐reactivity of HLA‐B27 monoclonal antibodies (mAbs) is a major problem.MethodsWe analyzed cross‐reactivity patterns
Levering, WHBM +4 more
openaire +4 more sources
CD28 and CTLA4 polymorphisms associated with ankylosing spondylitis: a study in the context of HLA-B27 [PDF]
Background The human leukocyte antigen (HLA)-B27 gene is highly associated with ankylosing spondylitis (AS). However, not everyone who carries the HLA-B27 antigen develops AS, indicating that factors beyond the HLA-B27 gene contribute to the disease’s ...
Kuang-Hui Yu +5 more
doaj +2 more sources

