Results 121 to 130 of about 12,194 (179)

Biochemical analysis of variant HLA-B27 antigens

Human Immunology, 1983
Biochemical analysis of HLA-B27 antigens from individuals that are HLA-ABC identical by serology but distinct in CML typing establishes that two types of HLA-B27 can be defined biochemically. The division of HLA-B27 into a W type and a K type by CML typing correlates perfectly with the biochemical data. HLA-B27 K type possesses a more basic isoelectric
H H, Mölders, M H, Breuning, P, Ivanyi, H L, Ploegh   +3 more
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Non-Antigen Presenting Effects of HLA-B27

Current Molecular Medicine, 2004
Spondyloarthropathies (SpA) are a group of chronic rheumatic diseases, which show a strong asoociation with human leukocyte antigen (HLA)-B27. Although the association between HLA-B27 and the susceptibility to SpA was discovered thirty years ago, the exact mechanism by which HLA-B27 predisposes to disease development remains unclear. The classical role
Markus A, Penttinen, Päivi, Ekman, Kaisa, Granfors   +2 more
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Antigen Report: HLA-B27

1984
As in the previous Workshops, HLA-B27 appears to be one of the best defined antigens. Four sera are very good or excellent (Table 1) as, indicated by their quality scores based on the formula of Mickey and Terasaki. The few extra reactions of the above-mentioned sera are cross-reactions, mostly with B7.
B. S. Breur, P. Ivanyi
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Microbial antigens mediate HLA-B27 diseases via TLRs

Journal of Autoimmunity, 2009
HLA-B27 positive individuals are predisposed to reactive arthritis developing 1-3 weeks after urogenital and gastrointestinal infections. Also ankylosing spondylitis (AS) associates strongly to HLA-B27, but no specific infection, Klebsiella pneumoniae excluded, has been linked to it.
Raimo, Pöllänen, Tarvo, Sillat, Jukka, Pajarinen, Jaakko, Levón, Emilia, Kaivosoja, Yrjö T, Konttinen   +5 more
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Association of HLA-B27 Antigen with Retroperitoneal Fibrosis

Journal of Urology, 1978
This is the second known case of retroperitoneal fibrosis in a middle-aged black man whose tissue type was HLA-B27 positive. The HLA-B27 antigen is present in only 4 per cent of black American male subjects and may be important in the diagnosis and management of patients with primary retroperitoneal fibrosis.
M K, Willscher, D E, Novicki, W F, Cwazka   +2 more
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Typing of serum‐soluble HLA‐B27 antigen by ELISA

Tissue Antigens, 1993
Abstract: An ELISA using serum as soluble HLA antigen source was developed for HLA‐B27 typing. Two sandwich assays were run in parallel. The first assay utilized a monoclonal antibody (mAb) reacting with a determinant expressed by both HLA‐B7 and B27 antigens; the other assay utilized a mAb reactive with HLA‐B7 antigens but not with HLA‐B27 antigens ...
P, Pouletty, C, Chang, J, Kalil, E, Atwood, S, Ferrone, B, Shimizu, W, Howson, R, Mazaheri, B, Del Villano, C, Grumet   +9 more
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Biochemical Features of HLA-B27 and Antigen Processing

2009
The strong association of the human MHC class I allele HLA-B27 with the development of the chronic inflammatory disease ankylosing spondylitis (AS) is clear and has been known for over three decades. Despite this, it is far from clear how HLA-B27 is directly involved in AS.
Simon J, Powis, Susana G, Santos, Antony N, Antoniou   +2 more
openaire   +2 more sources