Results 21 to 30 of about 93,215 (258)

Disease characteristics of HLA-B27 positive and negative finnish patients with juvenile idiopathic arthritis - results of the 18-year cohort follow-up study

Pediatric Rheumatology Online Journal, 2023
Background The aim of this long-term follow-up study was to compare the disease characteristics of HLA-B27 positive and negative patients with juvenile idiopathic arthritis (JIA).
Suvi Oili Orvokki Peltoniemi, Mia Glerup, Pekka Lahdenne, Kari K Eklund, Kristiina Aalto   +4 more
doaj   +1 more source

Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules

Frontiers in Immunology, 2022
Peptide-loaded Major Histocompatibility Complex (pMHC) class I molecules can be expressed in a single chain trimeric (SCT) format, composed of a specific peptide fused to the light chain beta-2 microglobulin (β2m) and MHC class I heavy chain (HC) by ...
Izabela Lenart, Izabela Lenart, Izabela Lenart, Linh-Huyen Truong, Linh-Huyen Truong, Dinh Dung Nguyen, Dinh Dung Nguyen, Olga Rasiukienė, Edward Tsao, Jonathan Armstrong, Pankaj Kumar, Kirsty McHugh, Kirsty McHugh, Branca I. Pereira, Branca I. Pereira, Branca I. Pereira, Balraj S. Maan, Balraj S. Maan, Malgorzata A. Garstka, Paul Bowness, Neil Blake, Simon J. Powis, Keith Gould, Darren Nesbeth, Antony N. Antoniou, Antony N. Antoniou   +25 more
doaj   +1 more source

Clinical picture of ankylosing spondylitis in HLA-B27 positive and negative patients

Современная ревматология, 2023
The link between the HLA-B27 gene and ankylosing spondylitis (AS) has been known for almost 50 years. During this time, it has been discovered that some of the clinical manifestations of the disease are uniformly associated with the disease in almost all
Sh. F. Erdes, K. V. Sakharova
doaj   +1 more source

Targeted delivery of an antigenic peptide to the endoplasmic reticulum: application for development of a peptide therapy for ankylosing spondylitis. [PDF]

PLoS ONE, 2013
The development of suitable methods to deliver peptides specifically to the endoplasmic reticulum (ER) can provide some potential therapeutic applications of such peptides.
Hui-Chun Yu, Ming-Chi Lu, Chin Li, Hsien-Lu Huang, Kuang-Yung Huang, Su-Qin Liu, Ning-Sheng Lai, Hsien-Bin Huang   +7 more
doaj   +1 more source

Arthritis in Cystic Fibrosis-Comparison of a Single-Center Cohort and Published Case Reports/Series and a Review of the Literature. [PDF]

APMIS
ABSTRACT Cystic fibrosis (CF) is commonly associated with musculoskeletal issues including inflammatory arthritis, CF arthritis. We present a retrospective cohort study which aims to describe the clinical characteristics, prevalence, and demographic associations of CF arthritis using both a clinical and literature cohort.
Peretz ASR, Bryrup T, Faurholt-Jepsen D, Nielsen CTH.   +3 more
europepmc   +2 more sources

Positivity and genotype distribution of HLA-B27 antigen in 7 829 patients with suspected ankylosing spondylitis

Di-san junyi daxue xuebao, 2020
Objective To analyze the positivity of human leukocyte surface antigen-B27 (HLA-B27) in patients with suspected ankylosing spondylitis (AS) and their relatives in Chongqing to understand the gender-specific distribution of HLA-B27 genotypes in the ...
GAO Lenyu, WU Hong, YOU Qingxia, WANG Yong   +3 more
doaj   +1 more source

Interaction between HLA-B60 and HLA-B27 as a Better Predictor of Ankylosing Spondylitis in a Taiwanese Population. [PDF]

PLoS ONE, 2015
Ankylosing spondylitis (AS) is a form of chronic inflammatory spondyloarthritis (SpA) that causes pain and stiffness in spines or joints. Human leukocyte antigen B27 (HLA-B27) and B60 (HLA-B60) have been reported as major genetic risk factors of AS.
James Cheng-Chung Wei, Henry Wong Sung-Ching, Yu-Wen Hsu, Ya-Feng Wen, Wen-Chang Wang, Ruey-Hong Wong, Hsing-Fang Lu, Floris A van Gaalen, Wei-Chiao Chang   +8 more
doaj   +1 more source

HLA-B27 Antigen Measurement

Definitions, 2020
The of the amount of HLA-B27 antigen present in a sample.

semanticscholar   +1 more source

Mimicry of human histocompatibility HLA-B27 antigens by Klebsiella pneumoniae [PDF]

Infection and Immunity, 1986
Anti-HLA-B27 monoclonal antibody M2, which was relatively specific for human histocompatibility antigen HLA-B27, was used to test several bacteria, some of which could potentially induce chronic arthritis in HLA-B27-positive individuals. Using the Western blot procedure, we observed positive reactions with 80,000- and 60,000-dalton antigens with one ...
Minoru Ogasawara, D H Kono, David Tak Yan Yu   +2 more
openalex   +4 more sources

Seasonal Variation in HLA-B27 Associated Uveitis. [PDF]

Clin Exp Ophthalmol
ABSTRACT Background To examine if there was a monthly variation in HLA‐B27‐associated uveitis. Methods Retrospective review of all individuals presenting to a single centre with HLA‐B27‐associated uveitis from 2009 to 2020. Results 577 participants with HLA‐B27‐associated uveitis were included. The median age at presentation was 40.4 years (IQR 31.1–51.
Samalia PD, Brodie J, Sims JL, Niederer RL.   +3 more
europepmc   +2 more sources