Results 61 to 70 of about 12,194 (179)
Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones
Arthritis &Rheumatology, Volume 78, Issue 1, Page 152-165, January 2026.Objective Psoriatic arthritis (PsA) is an HLA class I–associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T cell phenotype and clonality.
Lucy E. Durham +14 more
wiley +1 more source
Human Leukocyte Antigen-B27 and Disease Susceptibility in Vojvodina, Serbia
Balkan Journal of Medical Genetics, 2012 There are numerous studies showing the role of human leukocyte antigens (HLAs) related with susceptibility or resistance to certain diseases.
Vojvodić S. +2 more
doaj +1 more source
Glia, Volume 74, Issue 1, January 2026.C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli +12 more
wiley +1 more source
Mediators of Inflammation, 2017 Ankylosing spondylitis (AS) is highly associated with the expression of human leukocyte antigen-B27 (HLA-B∗27). HLA-B∗27 heavy chain (B27-HC) has an intrinsic propensity to fold slowly, leading to the accumulation of the misfolded B27-HC in the ...
Hui-Chun Yu +6 more
doaj +1 more source
Namık Kemal Tıp DergisiAim: This study aimed to evaluate the frequency of human leukocyte antigen (HLA)-B27 positivity and its clinical correlations in Turkish patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated ...
Dilara BULUT GÖKTEN +3 more
doaj +1 more source
HLA B27 y las espondilartropatías seronegativas
Revista Cubana de Medicina, 1997 Se realizó el tipaje serológico para el antígeno HLA B27 a 19 pacientes con espondilartropatías seronegativas para conocer su relación y, de ellos, 6 resultaron positivos; 94 individuos sanos conformaron el grupo control y en 4 se encontró el antígeno ...
Modesto González Cortiñas +3 more
doaj
CLINICAL COURSE OF JUVENILE IDIOPATHIC ARTHRITIS IN HLA-B27-POSITIVE PATIENTS IN ADULTHOOD
Медична наука України, 2017 Relevance. The existence of associations between histocompatibility antigens and JIA variants has been proved. There is no consensus that the JIAs associated with HLA-B27 antigen are transformed in adulthood into other diseases for which it is necessary ...
M.B. Dzhus +3 more
doaj +1 more source
强直性脊柱炎患者HLA-B27、CRP和ESR的水平及相关性分析
Zhongguo shiyan zhenduanxue, 2013 目的探讨强直性脊柱炎（AS）患者HLA-B27、CRP和ESR的水平及相关性。方法检测对54例AS患者和48例健康对照者人类白细胞抗原B27（Human leucocyte antigen B27,HLA-B27）血沉（ESR）、C反应蛋白（CRP）的水平,比较HLA-B27、CRP和ESR在AS的阳性率,探讨三者对AS诊断的相关性。结果 HLA-B27、CRP和ESR在AS患者阳性率分别为90.7%、85.1%、72.2%;AS患者和健康对照组HLA-B27、CRP和ESR的水平存在显著性差异 ...
祝文彩 +3 more
doaj
Expanding the Genetic Framework: Insights into Non-HLA-B27 Contributions to Axial Spondylarthritis
MedicinaBackground and Objectives: Spondylarthritis is a complex group of inflammatory diseases closely associated with the HLA-B27 antigen. However, the role of non-HLA-B27 alleles in the disease’s pathogenesis has gained significant scholarly attention in ...
Ruxandra-Elena Nagit +5 more
doaj +1 more source
Revista Brasileira de Reumatologia, 2006 Os sintomas articulares constituem a manifestação extra-intestinal mais comum em pacientes com doença de Crohn e com retocolite ulcerativa. Reconhecida como artrite colítica, e mais recentemente, artrite enteropática, está classificada como uma das ...
Cristina Costa Duarte Lanna +3 more
doaj +1 more source