Results 61 to 70 of about 12,247 (203)
International Journal of Cancer, Volume 157, Issue 10, Page 2156-2172, 15 November 2025.What's New? The anti‐aging protein klotho (KL) is a potential tumor suppressor and prognostic marker in glioblastoma. Little is known, however, about its mechanism of action and clinical relevance. This study examined KL expression in the setting of persistent inflammation and other stressors, including radiotherapy.
Andrea Galluzzo +19 more
wiley +1 more source
Mediators of Inflammation, 2017 Ankylosing spondylitis (AS) is highly associated with the expression of human leukocyte antigen-B27 (HLA-B∗27). HLA-B∗27 heavy chain (B27-HC) has an intrinsic propensity to fold slowly, leading to the accumulation of the misfolded B27-HC in the ...
Hui-Chun Yu +6 more
doaj +1 more source
Advanced Science, Volume 12, Issue 43, November 20, 2025.A matrix‐free human liver organoid–T cell co‐culture platform enables modeling of immune‐mediated drug‐induced liver injury (iDILI). Using flucloxacillin and patient‐matched cells, this system recapitulates HLA‐B*57:01–restricted CD8⁺ T cell activation and hepatocyte damage.
Fadoua El Abdellaoui Soussi +11 more
wiley +1 more source
Namık Kemal Tıp DergisiAim: This study aimed to evaluate the frequency of human leukocyte antigen (HLA)-B27 positivity and its clinical correlations in Turkish patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated ...
Dilara BULUT GÖKTEN +3 more
doaj +1 more source
Revista Brasileira de Reumatologia, 2006 Os sintomas articulares constituem a manifestação extra-intestinal mais comum em pacientes com doença de Crohn e com retocolite ulcerativa. Reconhecida como artrite colítica, e mais recentemente, artrite enteropática, está classificada como uma das ...
Cristina Costa Duarte Lanna +3 more
doaj +1 more source
CLINICAL COURSE OF JUVENILE IDIOPATHIC ARTHRITIS IN HLA-B27-POSITIVE PATIENTS IN ADULTHOOD
Медична наука України, 2017 Relevance. The existence of associations between histocompatibility antigens and JIA variants has been proved. There is no consensus that the JIAs associated with HLA-B27 antigen are transformed in adulthood into other diseases for which it is necessary ...
M.B. Dzhus +3 more
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HLA B27 y las espondilartropatías seronegativas
Revista Cubana de Medicina, 1997 Se realizó el tipaje serológico para el antígeno HLA B27 a 19 pacientes con espondilartropatías seronegativas para conocer su relación y, de ellos, 6 resultaron positivos; 94 individuos sanos conformaron el grupo control y en 4 se encontró el antígeno ...
Modesto González Cortiñas +3 more
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Expanding the Genetic Framework: Insights into Non-HLA-B27 Contributions to Axial Spondylarthritis
MedicinaBackground and Objectives: Spondylarthritis is a complex group of inflammatory diseases closely associated with the HLA-B27 antigen. However, the role of non-HLA-B27 alleles in the disease’s pathogenesis has gained significant scholarly attention in ...
Ruxandra-Elena Nagit +5 more
doaj +1 more source
Differences in lymphocyte typing for the antigen HLA-B27 resulting from the particular technique used in patients with ankylosing spondylitis [PDF]
, 1997 E Collantes-Estevez
openalex +1 more source
强直性脊柱炎患者HLA-B27、CRP和ESR的水平及相关性分析
Zhongguo shiyan zhenduanxue, 2013 目的探讨强直性脊柱炎（AS）患者HLA-B27、CRP和ESR的水平及相关性。方法检测对54例AS患者和48例健康对照者人类白细胞抗原B27（Human leucocyte antigen B27,HLA-B27）血沉（ESR）、C反应蛋白（CRP）的水平,比较HLA-B27、CRP和ESR在AS的阳性率,探讨三者对AS诊断的相关性。结果 HLA-B27、CRP和ESR在AS患者阳性率分别为90.7%、85.1%、72.2%;AS患者和健康对照组HLA-B27、CRP和ESR的水平存在显著性差异 ...
祝文彩 +3 more
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