Results 61 to 70 of about 93,215 (258)
Rat models of autoimmune uveitis [PDF]
, 2008 Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Diedrichs-Moehring, Maria +2 more
core +1 more source
Annals of the Academy of Medicine, Singapore, 2019 INTRODUCTION Ankylosing spondylitis (AS) and Behçet's disease are known to be associated with the human leukocyte antigen (HLA)-B27 and HLA-B51 genes, respectively. However, many of their clinical findings-including articular and extra-articular symptoms-
J. Jung +4 more
semanticscholar +1 more source
HLA‐B27 association of autoimmune encephalitis induced by PD‐L1 inhibitor
Annals of Clinical and Translational Neurology, 2020 While immune checkpoint inhibitors are increasingly used for various cancers, unpredictable immune‐related adverse events (irAEs) such as autoimmune encephalitis is life‐threatening.
Hyeyeon Chang +5 more
semanticscholar +1 more source
Histopathology of the gut in rheumatic diseases [PDF]
, 2018 The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F. +4 more
core +1 more source
A case of reactive arthritis after enteritis in in a 12-year-old boy [PDF]
Korean Journal of Pediatrics, 2011 Reactive arthritis comprises a subgroup within infection-associated arthritides in genetically susceptible hosts. Researchers and clinicians recognize two clinical forms of reactive arthritis which occurs after genitourinary tract infection and after ...
Peter Chun +3 more
doaj +1 more source
Microbiota and chronic inflammatory arthritis. an interwoven link [PDF]
, 2016 Background: Only recently, the scientific community gained insights on the importance of the intestinal resident flora for the host's health and disease.
D'Amelio, Raffaele +3 more
core +2 more sources
An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy
Advanced Science, EarlyView.This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma +14 more
wiley +1 more source
BMC Genomics, 2010 Background Human leukocyte antigen (HLA)-B27 is strongly associated with the development of reactive arthritis (ReA) in humans after salmonellosis. Human monocytic U937 cells transfected with HLA-B27 are less able to eliminate intracellular Salmonella ...
Hinton Jay CD +4 more
doaj +1 more source
RMD Open, 2023 Objective To describe and analyse the initial symptoms attributable to patients with spondyloarthritis (SpA) and their association with HLA-B27 status.Methods This was an observational, cross-sectional and multicentre study with patients who fulfilled ...
Jordi Gratacós +8 more
doaj +1 more source
HLA-B27 Positivity: associated health implications [PDF]
, 2011 HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct ...
Cox, C. L. +4 more
core +1 more source