Results 21 to 30 of about 2,477 (110)

Neuro-Behçet’s Disease Onset in the Context of Tuberculous Meningoencephalitis: A Case Report

open access: yesMedicina, 2023
Behçet’s disease (BD) is a systemic vasculitis that frequently presents with a relapsing–remitting pattern. CNS involvement (Neuro-Behçet) is rare, affecting approximately 10% of patients. Its etiological mechanisms are not yet fully understood. The most
Florian Antonescu   +8 more
doaj   +1 more source

Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease

open access: yesFrontiers in Immunology, 2019
Behçet's disease (BD) is an immune-mediated vasculitis related to imbalances between the innate and adaptive immune response. Infectious agents or environmental factors may trigger the disease in genetically predisposed individuals.
Ángel Castaño-Núñez   +20 more
doaj   +1 more source

Human Leukocyte Antigen-B51 Association and Behcet’s Disease in Saudi Arabia

open access: yesAnnals of Rheumatology and Autoimmunity
Introduction: Behcet’s disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology, characterized by recurrent oral ulcers, genital ulcers, skin lesions, ocular lesions, and other systemic manifestations.
Khalid A. Qushmaq   +4 more
doaj   +1 more source

Impacts of HLA Genetics on the SARS-CoV-2 Spike Proteins in the Arabian Population

open access: yesCOVID
(1) Background: Human Leukocyte Antigen (HLA) genetics substantially affect viral infection outcomes. SARS-CoV-2 continues to evolve, potentially escaping HLA presentation and hindering immune control.
Amal Haraka   +2 more
doaj   +1 more source

A Case of Human Leukocyte Antigen (HLA) B27-Positive Intestinal Behçet's Disease with Crohn's Disease-Like Anal Fistulas

open access: yesClinical Medicine Insights: Case Reports, 2014
A 49-year-old male was admitted to our hospital with complaints of perianal pain, bloody stool, and high-grade fever due to perianal abscess. Drainage was carried out; however, the patient's complaints worsened, and biopsy findings of colonoscopy showed ...
Tsuyoshi Kobashigawa   +5 more
doaj   +1 more source

Neuro-Bechet’s disease: a case series from India

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Background There are several studies which have studied large cohort of Neuro-Bechet’s disease (NBD) patients worldwide However, there is sparse literature about NBD from India.
Rohan R. Mahale   +5 more
doaj   +1 more source

Acometimento vascular na doença de Behçet: o processo imunopatológico

open access: yesJornal Vascular Brasileiro, 2021
Resumo A doença de Behçet constitui uma forma rara de vasculite sistêmica, que acomete de pequenos a grandes vasos. É caracterizada por manifestações mucocutâneas, pulmonares, cardiovasculares, gastrointestinais e neurológicas. Sua apresentação clínica é
Raquelle Machado de Vargas   +6 more
doaj   +2 more sources

Behcet’s Disease; do natural killer cells play a significant role?

open access: yesFrontiers in Immunology, 2015
Behçet's Disease is a complex inflammatory disease, of unknown aetiology. While disease pathogenesis remains unclear, a strong relationship between Behçet’s Disease and HLA-B*51 has been established over the last 30 years.
Harry ePetrushkin   +4 more
doaj   +1 more source

ASSOTIATIONS OF PECULIARITIES OF HLA-PHENOTYPE AND THE SENSIBILITY TO THE CORTICOSTEROID TREATMENT IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS WITH NEPHROTIC SYNDROME

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2017
The purpose of study was determination of HLA -antigens I and II classes as predictors of ineffectiveness of initial steroid therapy, and according prognozonegative markers of chronic glomerulonephritis with nephrotic syndrome. Methods. In 59 chronic
M. Kolesnyk   +4 more
doaj   +1 more source

ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes

open access: yesImmunology, Volume 177, Issue 2, Page 398-412, February 2026.
ERAP1 is an intracellular aminopeptidase that edits antigenic peptides to be presented by MHC class I molecules and is found in distinct functional allotypes in individuals. To investigate how different disease‐associated ERAP1 allotypes affect the cellular immunopeptidome, we generated A375 melanoma cell clones carrying either allotype 2 or allotype ...
Martha Nikopaschou   +6 more
wiley   +1 more source

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