Results 11 to 20 of about 101,671 (163)

Human Leukocyte Antigen-B51 Association and Behcet’s Disease in Saudi Arabia

Annals of Rheumatology and Autoimmunity
Introduction: Behcet’s disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology, characterized by recurrent oral ulcers, genital ulcers, skin lesions, ocular lesions, and other systemic manifestations.
Khalid A. Qushmaq, Majed R. Albirdisi, Mohannad M. AlAsiri, Ahmad I. Andijani, Abdullah AlJurayyan   +4 more
doaj   +2 more sources

Atypical Thrombotic Presentation of Behçet's Disease

Case Reports in Vascular Medicine
As Behçet's disease (BD) is a multisystem disorder that affects blood vessels, it predisposes patients to an increased risk of thrombosis. The vessels most commonly involved are those of the lower extremities, although the dural venous system may also be
Hakeem Asad, Georges El Hasbani, Kenneth J. Warrington   +2 more
doaj   +2 more sources

Frequency of HLA-B5, HLA-B51 and HLA-B27 in patients with idiopathic uveitis and Behçet's disease: a case-control study. [PDF]

Reumatologia, 2018
ObjectivesIdiopathic uveitis is the most common form of uveitis in most countries. Uveitis affects about 40–80% of patients with Behçet’s disease (BD). Class I, HLA-B5, and its subclass B51 allele have the strongest association with BD, but its role in ...
Shenavandeh S, Jahanshahi KA, Aflaki E, Tavassoli A.   +3 more
europepmc   +2 more sources

Clinical Images: Chronic nonbacterial osteomyelitis associated with inflammatory bowel disease. [PDF]

ACR Open Rheumatol
ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Xu C, Shi Y, Zhang W, Han Y.
europepmc   +2 more sources

Retrospective analysis of cutaneous immune-related adverse events following checkpoint inhibitor therapy in melanoma patients reveals increased risk associated with the HLA-B*51:01 allele. [PDF]

Cancer
ABSTRACT Background While immune checkpoint inhibitors (ICIs) have shown significant efficacy, a common side effect is cutaneous immune‐related adverse events (irAEs). This study focuses on exploring the association between specific human leukocyte antigen (HLA) alleles and the development of cutaneous irAEs in melanoma patients undergoing ICI ...
DiLeo M, Oglesby S, Leung CH, Pauken KE, Farooq S, Haydu LE, Kubicki SL, Martinez R, Welborn M, Zahiruddin S, Zou J, Cao K, Patel AB.   +12 more
europepmc   +2 more sources

Multilayered defense in HLA-B51-associated HIV viral control. [PDF]

J Immunol, 2011
Polymorphism in the HLA region of a chromosome is the major source of host genetic variability in HIV-1 outcome, but there is limited understanding of the mechanisms underlying the beneficial effect of protective class I alleles such as HLA-B57, -B27 ...
Zhang Y, Peng Y, Yan H, Xu K, Saito M, Wu H, Chen X, Ranasinghe S, Kuse N, Powell T, Zhao Y, Li W, Zhang X, Feng X, Li N, Leligdowicz A, Xu X, John M, Takiguchi M, McMichael A, Rowland-Jones S, Dong T.   +21 more
europepmc   +2 more sources

Keratoscleritis and Choroidal Exudative Detachment in the Setting of Ocular Pyoderma Gangrenosum. [PDF]

Case Rep Ophthalmol Med
Purpose The purpose of this study is to report a rare case of ocular pyoderma gangrenosum (PG) presenting as keratoscleritis with choroidal effusion following cataract surgery and to highlight its clinical recognition and management. Methods A 79‐year‐old man developed a corneal ulcer 2 days after uncomplicated phacoemulsification with intraocular lens
Bodeen J, El Zein L, Yamanuha JJ, Chanbour W.   +3 more
europepmc   +2 more sources

Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]

, 1989
Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Tabaczewski, P., Pohla, Heike, Heike Pohla, Kuon, W., Wolfgang Kuon, Piotr Tabaczewski, Doerner, C., Weiss, Elisabeth H., Christa Doerner, Elisabeth H. Weiss   +9 more
core   +1 more source

Impact of HLA-B51 on uveitis and retinal vasculitis: data from the AIDA International Network Registries on ocular inflammatory disorders [PDF]

, 2023
Background: Non-infectious uveitis (NIU) represents a difficult-to-manage condition characterized by intraocular inflammation that can potentially cause irreversible ocular damage, ultimately leading to a poor visual outcome.
Sota, Jurgen
core   +1 more source

Episcleritis; and posterior uveitis misdiagnosed as orbital cellulitis in a child patient with Behçet’s disease

SAGE Open Medical Case Reports, 2023
Behçet’s disease is a chronic multisystem vasculitis that presented with several manifestations. Episcleritis is a benign inflammation of the episcleral tissue and is rarely reported in Behçet’s disease.
Mohsen Jari, Shidrokh Nasiri, Mohammadreza Ghandehari   +2 more
doaj   +1 more source