Results 31 to 40 of about 2,566 (126)
The purpose of study was determination of HLA -antigens I and II classes as predictors of ineffectiveness of initial steroid therapy, and according prognozonegative markers of chronic glomerulonephritis with nephrotic syndrome. Methods. In 59 chronic
M. Kolesnyk +4 more
doaj +1 more source
A 40-year-old woman presented with fever, polyarthritis, and a recurrent rash on the trunk and thighs. She was initially diagnosed with adult-onset Still’s disease (AOSD) based on elevated serum ferritin and matrix metalloproteinase-3, and on normal ...
Motoo Kikuchi, Rena Oda, Hirotaka Ohara
doaj +1 more source
Objectives: This study aims to investigate the separate and cumulative effects of smoking and human leukocyte antigen (HLA)-B51 on the severity and clinical manifestations of Behçet’s disease (BD).
Serpil TUNA +2 more
doaj
Neuro-Bechet’s disease: a case series from India
Background There are several studies which have studied large cohort of Neuro-Bechet’s disease (NBD) patients worldwide However, there is sparse literature about NBD from India.
Rohan R. Mahale +5 more
doaj +1 more source
Dupilumab Treatment in Pemphigus: A Report of Three Cases and Literature Review
Capsule summary Pemphigus vulgaris and foliaceus are rare autoimmune blistering diseases traditionally treated with corticosteroids, immunosuppressants, intravenous immunoglobulins, and rituximab. A subset of patients remains refractory or has contraindications to these conventional therapies. We present three cases of pemphigus treated with dupilumab.
José Javier Mateos Rico +5 more
wiley +1 more source
deltaHED predicts survival and immune evasion in PD‐1 blockade therapy: a multi‐cohort study across three cancer types. deltaHED quantifies germlinesomatic HLA‐I divergence and predicts survival and immune evasion in PD‐1 blockade therapy. Across nasopharyngeal carcinoma, melanoma, and esophageal squamous cell carcinoma, high deltaHED is associated ...
Jianying Xu +10 more
wiley +1 more source
ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes
ERAP1 is an intracellular aminopeptidase that edits antigenic peptides to be presented by MHC class I molecules and is found in distinct functional allotypes in individuals. To investigate how different disease‐associated ERAP1 allotypes affect the cellular immunopeptidome, we generated A375 melanoma cell clones carrying either allotype 2 or allotype ...
Martha Nikopaschou +6 more
wiley +1 more source
Dactilitis and oligoarthritis after BCG immunotherapy in a patient affected by bladder cancer
The treatment of bladder cancer with Bacillus of Calmette-Guerin (BCG) immunotherapy can induce the appearance of a reactive disorder. The Authors describe a 55-year-old male patient with bladder cancer treated with endovesical instillation of BCG ...
N. Elkhaldi +4 more
doaj +1 more source
Human leukocyte antigen-associated uveitis in Thai population: Brief review
Human Leukocyte Antigen (HLA) has been associated with several immune-mediated diseases, malignancies and infectious diseases. Due to the HLA complexity and polymorphisms, several types of HLA have been used as the molecular markers in diagnosis.
Nampeung Anukul +2 more
doaj
The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei +4 more
wiley +1 more source

