Results 41 to 50 of about 101,671 (163)

Clinical manifestations of HLA B51 (5) positive patients in University Hospital of Split

, 2021
Cilj istraživanja: Cilj ovog istraživanja je bio utvrditi kliničke manifestacije HLA B51(5) pozitivnih bolesnika u populaciji bolesnika koji su pregledani u poliklinici, dnevnoj bolnici te stacionaru Zavoda za reumatologiju i kliničku imunologiju ...
Madunić, Martina
core  

Acometimento vascular na doença de Behçet: o processo imunopatológico

Jornal Vascular Brasileiro, 2021
Resumo A doença de Behçet constitui uma forma rara de vasculite sistêmica, que acomete de pequenos a grandes vasos. É caracterizada por manifestações mucocutâneas, pulmonares, cardiovasculares, gastrointestinais e neurológicas. Sua apresentação clínica é
Raquelle Machado de Vargas, Maria Luiza Nunes da Cruz, Maria Paula Hashimoto Giarllarielli, Beatriz Mota Sano, Geovana Idelfoncio da Silva, Karina Furlani Zoccal, Cristiane Tefé-Silva   +6 more
doaj   +2 more sources

deltaHED predicts survival and immune evasion in PD‐1 blockade therapy: A multi‐cohort study across three cancer types

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
deltaHED predicts survival and immune evasion in PD‐1 blockade therapy: a multi‐cohort study across three cancer types. deltaHED quantifies germlinesomatic HLA‐I divergence and predicts survival and immune evasion in PD‐1 blockade therapy. Across nasopharyngeal carcinoma, melanoma, and esophageal squamous cell carcinoma, high deltaHED is associated ...
Jianying Xu, Xiaoli Wei, Jicheng Yao, Ujjwal Mukund Mahajan, Ulf Dietrich Kahlert, Run Shi, Kaiying Zhang, Ahmed Alnatsha, Zhengyi Qian, Fei Han, Fenghua Wang   +10 more
wiley   +1 more source

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]

, 1998
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan, Matthias Ulbrecht, Ulbrecht, Matthias, Coligan, John E., Andrew G. Brooks, Brooks, AG, Borrego, F, Coligan, JE, Elisabeth H. Weiss, Brooks, Andrew G., Francisco Borrego, Borrego, Francisco, Weiss, Elisabeth H., Ulbrecht, M, Weiss, EH   +14 more
core   +1 more source

ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes

Immunology, Volume 177, Issue 2, Page 398-412, February 2026.
ERAP1 is an intracellular aminopeptidase that edits antigenic peptides to be presented by MHC class I molecules and is found in distinct functional allotypes in individuals. To investigate how different disease‐associated ERAP1 allotypes affect the cellular immunopeptidome, we generated A375 melanoma cell clones carrying either allotype 2 or allotype ...
Martha Nikopaschou, Martina Samiotaki, Anna Kannavou, Nikolaos V. Angelis, Ourania Tsitsilonis, George Panayotou, Efstratios Stratikos   +6 more
wiley   +1 more source

Identification of a naturally processed NY-ESO-1 peptide recognized by CD8+ T cells in the context of HLA-B51 [PDF]

, 2002
NY-ESO-1 is one of the most immunogenic cancer antigens known to date, inducing humoral and cellular immune responses in a high proportion of patients with advanced NY-ESO-1-expressing cancers.
Knuth, Alexander, Gnjatic, Sacha, Karbach, Julia, Stockert, Elisabeth, Old, Lloyd J, Skipper, Jonathan, Arand, Michael; https://orcid.org/, Maeurer, Markus, Jäger, Elke, Chen, Yao-Tseng, Jäger, Dirk, Atmaca, Akin   +11 more
core   +1 more source

Dactilitis and oligoarthritis after BCG immunotherapy in a patient affected by bladder cancer

Reumatismo, 2011
The treatment of bladder cancer with Bacillus of Calmette-Guerin (BCG) immunotherapy can induce the appearance of a reactive disorder. The Authors describe a 55-year-old male patient with bladder cancer treated with endovesical instillation of BCG ...
N. Elkhaldi, L. Bernardini, C.U. Manzini, M.T. Mascia, C. Ferri   +4 more
doaj   +1 more source

Primary Immunodeficiency Disease Mimicking Pediatric Bechet’s Disease

Children, 2021
Behcet’s disease (BD) is a chronic inflammatory disease with multisystemic involvement. Its etiology is considered to involve complex environmental and genetic factors. Several susceptibility genes for BD, such as human leukocyte antigen (HLA)-A26, IL23R-
Mayuka Shiraki, Saori Kadowaki, Tomonori Kadowaki, Norio Kawamoto, Hidenori Ohnishi   +4 more
doaj   +1 more source

Epidemiology of human leukocyte antigens among omani population

Saudi Journal of Kidney Diseases and Transplantation, 2017
Oman is located on the Southeastern coast of the Arabian Peninsula, and its population has high levels of consanguinity. Human leukocytic antigen (HLA) typing analysis in human population holds unexploited potential for elucidating the genetic causes of ...
Issa Al Salmi, Abdul Massiah Metry, Faisal Al Ismaili, Alan Hola, Faissal Shaheen, Hana Fakhoury, Suad Hannawi   +6 more
doaj   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei, Hamid Pajavand, Razieh Shahbazi, Marzieh Rezaei, Elahe Taki   +4 more
wiley   +1 more source