Results 21 to 30 of about 2,566 (126)
Human Leukocyte Antigen-B51 Association and Behcet’s Disease in Saudi Arabia
Introduction: Behcet’s disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology, characterized by recurrent oral ulcers, genital ulcers, skin lesions, ocular lesions, and other systemic manifestations.
Khalid A. Qushmaq +4 more
doaj +1 more source
Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease
Behçet's disease (BD) is an immune-mediated vasculitis related to imbalances between the innate and adaptive immune response. Infectious agents or environmental factors may trigger the disease in genetically predisposed individuals.
Ángel Castaño-Núñez +20 more
doaj +1 more source
Impacts of HLA Genetics on the SARS-CoV-2 Spike Proteins in the Arabian Population
(1) Background: Human Leukocyte Antigen (HLA) genetics substantially affect viral infection outcomes. SARS-CoV-2 continues to evolve, potentially escaping HLA presentation and hindering immune control.
Amal Haraka +2 more
doaj +1 more source
When to consider an inborn error of immunity: clues for physicians
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
A 49-year-old male was admitted to our hospital with complaints of perianal pain, bloody stool, and high-grade fever due to perianal abscess. Drainage was carried out; however, the patient's complaints worsened, and biopsy findings of colonoscopy showed ...
Tsuyoshi Kobashigawa +5 more
doaj +1 more source
Neuro-Behçet’s Disease Onset in the Context of Tuberculous Meningoencephalitis: A Case Report
Behçet’s disease (BD) is a systemic vasculitis that frequently presents with a relapsing–remitting pattern. CNS involvement (Neuro-Behçet) is rare, affecting approximately 10% of patients. Its etiological mechanisms are not yet fully understood. The most
Florian Antonescu +8 more
doaj +1 more source
Neuro‐Behçet's Disease and Psychiatric Disorders: From a Case Report to a Systematic Review
ABSTRACT Background Behçet's disease is a chronic, relapsing systemic vasculitis that can affect multiple organ systems. Neurological involvement, known as neuro‐Behçet's disease, occurs in a subset of patients, while psychiatric manifestations—termed neuro‐psycho Behçet's disease—remain poorly characterized.
Jorge Renau +5 more
wiley +1 more source
ABSTRACT A 12‐year‐old boy presented with recurrent oral and scrotal ulcers, papulopustular lesions, arthralgia, and a positive pathergy test. Autoimmune tests were negative; ophthalmologic and gastrointestinal assessments were reassuring. Topical therapy and colchicine produced sustained improvement.
Fares Basel Abu Taha +8 more
wiley +1 more source
Comparison of epidemiologic, clinical, laboratory, imaging, and treatment response features in 59 patients with Takayasu Arteritis (TAK) and 37 with Giant Cell Arteritis (GCA, 7 C‐GCA, 30 LV‐GCA) at diagnosis and during follow‐up demonstrates that these are distinct diseases, warranting disease‐specific diagnostic and therapeutic approaches.
Marcella Prete +13 more
wiley +1 more source
Behcet’s Disease; do natural killer cells play a significant role?
Behçet's Disease is a complex inflammatory disease, of unknown aetiology. While disease pathogenesis remains unclear, a strong relationship between Behçet’s Disease and HLA-B*51 has been established over the last 30 years.
Harry ePetrushkin +4 more
doaj +1 more source

