Results 21 to 30 of about 101,671 (163)

HLA-B51 associated HIV-1 viral control

open access: yes, 2013
Polymorphism in the Human Leucocyte Antigen (HLA) region of chromosome is the major source of host genetic variability in outcome of HIV-1 infection. However, there is limited understanding of the mechanisms underlying the beneficial effect of protective
Peng, Yanchun
core   +2 more sources

Case report: Deep vein thrombosis as the sole clinical feature of Behcet’s syndrome

open access: yesFrontiers in Medicine, 2023
IntroductionBehcet’s syndrome is a rare, chronic, systemic condition often categorized within the group of vasculitides. It presents a diagnostic challenge due to its varied clinical manifestations and the absence of a definitive laboratory test.
Abdelrahman Omara   +7 more
doaj   +1 more source

Behcet's Disease and Ankylosing Spondylitis: A Rare Association

open access: yesIndian Journal of Medical Specialities, 2019
The overlap syndrome is frequently encountered in rheumatology, but the coexistence of Behçet's disease and ankylosing spondylitis is considered to be rare.
Amina Mounir   +4 more
doaj   +1 more source

Idiopathic Stroke

open access: yesPediatric Neurology Briefs, 1992
Of 4 children with idiopathic stroke syndrome examined at the Department of Neurosciences and Pediatrics, UMD-New Jersey Medical School and the University of Rochester Medical Center, all 4 were heterozygous for human leukocyte antigen (HLA-B51).
J Gordon Millichap
doaj   +1 more source

Transcriptome analysis of immune cells from Behçet’s syndrome patients: the importance of IL-17-producing cells and antigen-presenting cells in the pathogenesis of Behçet’s syndrome

open access: yesArthritis Research & Therapy, 2022
Background Behçet’s syndrome (BS) is an immune-mediated disease characterized by recurrent oral ulcers, genital ulcers, uveitis, and skin symptoms. HLA-B51, as well as other genetic polymorphisms, has been reported to be associated with BS; however, the ...
Mai Okubo   +16 more
doaj   +1 more source

Associations of HLA-A, -B and -DRB1 types with oral diseases in Swiss adults. [PDF]

open access: yesPLoS ONE, 2014
Human leukocyte antigens (HLA) are crucial components of host defense against microbial challenge but the associations of HLA types with oral infectious diseases have not been studied in detail.
Matti Mauramo   +5 more
doaj   +1 more source

Behçet's disease: review with emphasis on dermatological aspects [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Behçet's disease is a systemic vasculitis characterized by attacks of acute inflammation, which can affect almost every vascularized area of the body. There is a close correlation between the geographical distribution of HLA-B51 and its prevalence.
Maria Antonieta Rios Scherrer   +2 more
doaj   +1 more source

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

open access: yes, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V.   +5 more
core   +1 more source

Molecular dynamics simulations provide molecular insights into the role of HLA-B51 in Behcet's disease pathogenesis

open access: yes, 2020
Behcet's disease is an inflammatory disorder of unknown etiology. Genetic tendency has an important role in its pathogenesis, and HLA-B51, a class I MHC antigen, has been recognized as the strongest susceptibility factor for Behcet's disease. Despite the
Golcuk, Mert   +7 more
core   +1 more source

Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease

open access: yesFrontiers in Immunology, 2019
Behçet's disease (BD) is an immune-mediated vasculitis related to imbalances between the innate and adaptive immune response. Infectious agents or environmental factors may trigger the disease in genetically predisposed individuals.
Ángel Castaño-Núñez   +20 more
doaj   +1 more source

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