Results 241 to 250 of about 164,764 (309)

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

Allergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang, Telly Sepahpour, Stephanie Kortchak, Kirthiram Krishnaveni Sivakumar, Spyros Karaiskos, Ngoc Pham, Yura Jang, Montserrat Puig, Michael Norcross   +8 more
wiley   +1 more source

Positive B cell flow cytometry crossmatch without detectable donor-specific antibodies: true or false reactivity? [PDF]

Front Immunol
de Chickera SN, Al Agbar S, Sharma A, Beaune D, Sidahmed EA, Gunaratnam L, Sidahmed A.   +6 more
europepmc   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Integrative analysis of T cell subset-specific ICOS expression and tumor HLA class I/II expression in lung adenocarcinoma: implications for their interaction and clinical outcome. [PDF]

Cancer Immunol Immunother
Yamada H, Yamada R, Komohara Y, Pan C, Yoshii D, Yano H, Matsubara E, Shinchi Y, Tsukamoto H, Fujiwara Y, Ikeda K, Suzuki M.   +11 more
europepmc   +1 more source

Causal relationship between immune cells and idiopathic thrombocytopenic purpura: A bidirectional Mendelian randomization study

Rheumatology &Autoimmunity, EarlyView.
Heyi Zhang, Luyao Song, Ying Mao, Zerui Liu, Zhexi He, Mengxia Liu, Jingfang Zhang, Rui Zhao, Jing Luo, Shengxiao Zhang   +9 more
wiley   +1 more source

Decidual immune activation by extravillous trophoblasts drives maternal-fetal tolerance and immunity. [PDF]

Trends Immunol
Tilburgs T.
europepmc   +1 more source

Anti-HLA antibodies in lung transplantation: diagnostic pitfalls and future directions. [PDF]

Eur Respir Rev
Zajacova A, Revilla-Lopez E, Guney M, De Pelsmaeker S, Emonds MP, Naesens M, Saez-Gimenez B, Vanaudenaerde BM, Vos R.   +8 more
europepmc   +1 more source

Toward next-generation therapeutic HPV vaccines: A review on expanding the antigen repertoire and an integrated bioinformatics selection framework. [PDF]

Hum Vaccin Immunother
Zhang D, Guo S, Yuan J, Hu Y, Li K, Han Y.   +5 more
europepmc   +1 more source

Generation of effector cells from T cell subsets [PDF]

, 1979
Koszinowski, Ulrich H., Simon, M. M.
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