Results 71 to 80 of about 12,564,476 (214)

Peculiarities of HLA-phenotypes in patients with pyelonephritis

Annals of Mechnikov's Institute, 2020
Introduction. Of great interest are the studies on the role of human leucocyte antigens (HLA) in pathogenesis of a disease. The kidneys is vulnerable to injury in the context of inflammatory responses, with the potential involvement of a number of ...
F Haiseniuk, V Driyanska, V Kruglikov
doaj  

The Dıagnosıs of Human Leukocyte Antıgen Class I and Class II Allel ın Eastern Anatolıa Regıon

Van Tıp Dergisi, 2019
INTRODUCTION: The aim of our study was to investigate the frequency of HLA class I and class II alleles in Eastern Anatolia. METHODS: The study included 1050 unrelated bone marrow donors from the archives.
Eda Balkan, Ezgi Yaşar, Hasan Doğan
doaj   +1 more source

Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk [PDF]

, 2012
Objective: The identification of a vitamin D-responsive (VDRE) motif within the HLA-DRB1*15:01 promoter region provides an attractive explanation for the combined effects of HLA-DR inheritance and vitamin D exposure on multiple sclerosis (MS) risk.
Qiu, W., Nolan, D., Kermode, A., Tschochner, M., Mastaglia, F., Christiansen, F.T., Witt, C., Castley, A., James, I., Sayer, D., Carroll, W.   +10 more
core  

HLA-EpiCheck : A B-cell epitope prediction tool on HLA antigens using molecular dynamics simulation data

, 2023
International audienceIn the context of organ transplantation, recipient’s antibodies against donor-specific HLA antigens are the main reason for transplant loss.The prediction of B-cell (antibody) epitopes on HLA antigens is therefore a key challenge on
Usureau, Cedric, Marie-Dominique, Devignes, Amaya-Ramirez, Diego, Taupin, Jean-Luc, Lhotte, Romain, Smaïl-Tabbone, Malika, Devriese, Magali   +6 more
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CD4+ T cell epitopes of FliC conserved between strains of Burkholderia: implications for vaccines against melioidosis and cepacia complex in cystic fibrosis.

, 2014
Burkholderia pseudomallei is the causative agent of melioidosis characterized by pneumonia and fatal septicemia and prevalent in Southeast Asia. Related Burkholderia species are strong risk factors of mortality in cystic fibrosis (CF).
Nithichanon, Arnone, Lertmemongkolchai, Ganjana, Chu, Karen KY, Khaenam, Prasong, Rinchai, Darawan, Maillere, Bernard, Robinson, John H, Favry, Emmanuel, Bancroft, Gregory J, Reynolds, Catherine J, Altmann, Daniel M, Spink, Natasha, Boyton, Rosemary J, Musson, Julie A, De Soyza, Anthony   +14 more
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A new HLA-B*15 allele, HLA-B*15:263, identified in a Korean individual

, 2015
HLA-B*15:263 differs from HLA-B*15:18:01 by a single nucleotide exchange at position 824, C>G (codon 251 TCT>TGT ...
박금보래, 박용정, 김현숙
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HLA-A and HLA-B alleles associated in psoriasis patients from Mumbai, Western India

Indian Journal of Dermatology, 2011
Background: Psoriasis, a common autoimmune disorder characterized by T cell-mediated keratinocyte hyperproliferation, is known to be associated with the presence of certain specific Human Leukocyte Antigen (HLA) alleles.
Shankarkumar Umapathy, Aruna Pawar, R Mitra, D Khuperkar, J P Devaraj, K Ghosh, U Khopkar   +6 more
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Polimorfismos da região 3' não traduzida do gene HLA-G em pacientes com câncer de mama e controles no estado de Santa Catarina [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Biologia Celular e do DesenvolvimentoO câncer de mama é o segundo tipo de câncer mais frequente no mundo e de maior prevalência ...
Silva, Mariáh Damiani da
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Identification and biophysical characterization of Plasmodium peptide binding by common African HLAs

Scientific Reports
Human Leukocyte Antigens (HLA) are immunoreceptors that present peptide antigens at the cell surface to T cells as a primary mechanism of immune surveillance.
Marielle B. Frooman, Klara Choi, Maya Z. Kahn, Li-Yen Yang, Aubrielle Cunningham, Jenna M. RisCassi, Andrew C. McShan   +6 more
doaj   +1 more source

Novel BCR-Targeting Fusion Proteins for Antigen-Specific Depletion of Alloreactive B Cells in Antibody-Mediated Rejection

Cells
Donor-specific anti-HLA antibodies (DSAs) bind to donor vascular endothelial cells and mediate allograft rejection (AMR), but a clinical challenge for which targeted therapeutic options remain limited.
Jing Zhang, Leiyan Wei, Lei Song, Xiaofang Lu, Liang Tan, Xin Li, Li Fu, Qizhi Luo, Xubiao Xie, Yizhou Zou   +9 more
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