HLA matching of donors and recipients plays a major role in the success of organ transplantation. Race differences inHLA have been reported elsewhere. Aim: To analyse the diversity of HLA Class I and Class II among kidney donors and recipients according ...
AGH Assounga +3 more
doaj +1 more source
High sensitivity of human leukocyte antigen–B*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients [PDF]
Background. Although the human leukocyte antigen (HLA)-B*5701 is highly associated with a hypersensitivity reaction (HSR) to abacavir (ABC), variable sensitivities have been reported when clinical data alone have been used to define an ABC HSR.
Stancil, B. +13 more
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HLA typing in systemic sclerosis
Objective: the aim of the study was to investigate the relationship between Systemic Sclerosis (SSc) and HLA antigens, and to correlate these antigens with the clinical manifestations of the disease.
E. Favalli +4 more
doaj +1 more source
Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy +70 more
core +1 more source
Pre-treatment screening of individuals for human leukocyte antigens (HLA) HLA-B*57:01 is recommended for the prevention of life-threatening hypersensitivity reactions to abacavir, a drug widely prescribed for HIV treatment. However, the implementation of
Jianxiong Chan +10 more
doaj +1 more source
Studies on polymorphic alu insertions and genomic diversity within the major histocompatibility complex [PDF]
After the initiation of the human genome sequencing project and the introduction of the field of 'bioinformatics', interest in human genetic diversity studies has been increased.
Dunn, David Suliman
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HLA class I (-A, -B, -C) and class II (-DR, -DQ) polymorphism in the Mauritanian population
Background HLA antigens have been widely studied for their role in transplantation biology, human diseases and population diversity. The aim of this study was to provide the first profile of HLA class I and class II alleles in the Mauritanian population.
Cheikh Tijani Hamed +7 more
doaj +1 more source
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. [PDF]
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we
Klein, Michèl R +12 more
core +1 more source
Polimorfismos do gene HLA-G em pacientes com psoríase [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento.A psoríase é uma doença inflamatória crônica, de etiologia desconhecida, que afeta a pele e
Almeida, Bibiana Sgorla de
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HLA-C and HLA-DQB1 compatibility in unrelated cord blood transplants
BACKGROUND AND OBJECTIVE: Umbilical cord blood (UCB) cells have been definitively proved to be a source of hematopoietic stem cells with repopulating capacity when transplanted into pediatric hosts with neoplastic or non-neoplastic disease. Moreover, due
L Elia +9 more
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