A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers [PDF]
, 2012 Background and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV ...
Stefan Zeuzem +15 more
core +2 more sources
Assessment of TWIST1 as an immunotherapeutic target of cancer [PDF]
, 2011 CD8+ T lymphocytes are key mediators of anti-tumour immunity, eliminating tumour cells through the recognition of tumour antigens. Increasing the number of characterised tumour antigens, especially those with highly specific tumour expression, may enable
Poon, E.C.C.
core
HLA-A AND HLA-B ANTIGENS IN CHRONIC-BRONCHITIS
, 1993 The A- and B- types of Human Leucocyte Antigens (HLA) were examined in a group of Greek patients with a diagnosis of chronic bronchitis. The results were compared to those of 400 healthy unrelated controls (smokers and non-smokers) from the same population.
ANAGNOSTOPOULOU, U +4 more
openaire +1 more source
Vaccinia virus expressing ICP47 : a novel platform for cancer vaccines highlighting tumor epitopes and hiding viral antigens [PDF]
, 2010 Background Recombinant poxviruses expressing tumor associated antigens (TAAs) are evaluated since 20 years as immunogenic vaccine vector in clinical trials.
Raafat, Nermin Abdel Fattah
core +1 more source
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2005 Se realizó un estudio de la frecuencia fenotípica y génica de los antígenos del sistema principal de histocompatibilidad HLA en personas no relacionadas, supuestamente sanas, tomadas como muestra de la población cubana.
Luz M Morera Barrios +8 more
doaj
Seronegative spondyloarthropathies and HLA antigens in a Mestizo population
, 1984 HLA-A and -B antigens incidence were investigated in 100 cases of Seronegative Spondyloarthropathies and in 303 control individuals of a Venezuelan Mestizo population.
Bianco Colmenares, Nicolás E. +3 more
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Mapping the Landscape of Host-Pathogen Coevolution: HLA Class I Binding and Its Relationship with Evolutionary Conservation in Human and Viral Proteins [PDF]
, 2011 The high diversity of HLA binding preferences has been driven by the sequence diversity of short segments of relevant pathogenic proteins presented by HLA molecules to the immune system.
Jojic, N. +9 more
core
Analysis of Human Leukocyte Antigen Frequency among Renal Transplant Recipients and Donors in Nepal
Global Journal of Transfusion MedicineBackground and Objectives: Kidney transplants are effective for advanced renal failure, but graft rejection can occur when the recipient’s immune system misidentifies the kidney as a foreign object.
Rekha Manandhar +3 more
doaj +1 more source
Gemcitabine alters the proteasome composition and immunopeptidome of tumour cells
OncoImmunology, 2018 The antigenic makeup of tumour cells can have a profound effect on the progression of cancer and success of immunotherapies. Therefore, one strategy to improve the efficacy of cancer treatments is to augment the antigens displayed by tumours. The present
A. M. Gravett +4 more
doaj +1 more source
Glaucoma primario de ángulo abierto y HLA B35 Primary open-angle glaucoma and HLA B35
Revista Cubana de Hematología, Inmunología y Hemoterapia, 1999 Se determinó la frecuencia de 29 antígenos HLA de los loci A y B en 20 pacientes con glaucoma primario de ángulo abierto diagnósticados en el Servicio de Oftalmología del Hospital General Docente «Enrique Cabrera».
Luz M Morera Barrios +5 more
doaj