Results 251 to 260 of about 375,043 (313)

Long‐term Maintenance of HLA‐D Restricted T Cells Specific for Soluble Antigens

Scandinavian Journal of Immunology, 1980
Lymphocytes from donors sensitized to soluble protein antigens tuberculin (PPD) and tetanus toxoid were stimulated in vitro with these antigens. The blasts were isolated on density gradients and maintained in long‐term proliferating culture by the addition of supernatants from phytohaemagglutinin‐stimulated (PHA) cultures. Blasts can be shown to retain
J T, Kurnick, P, Altevogt, J, Lindblom, O, Sjöberg, A, Danneus, H, Wigzell   +5 more
openaire   +3 more sources

HLA–D and –DR antigens on human amniotic fluid cells

Tissue Antigens, 1983
Human amniotic fluid cells, known to express HLA–A, –B, and –C antigens, were tested for the presence of lymphocyte‐stimulating antigens (LD or HLA–D) using modifications of the mixed lymphocyte culture (MLC) and primed lymphocyte typing (PLT) tests. Peripheral blood lymphocytes were co‐cultured with various concentrations of allogeneic amniotic fluid ...
Elizabeth Valentine‐Thon, Gerlinde Kreeb, Hans Grosse‐Wilde, Eberhard Passarge   +3 more
openaire   +2 more sources

The Frequencies of HLA-D Antigens in the Population of SR Croatia

1986
Despite of the significant correlation between the majority of serologicaly defined HLA-DR antigens and HLA-D antigens defined by homozygous typing cells (HTC), the correlation between HLA-Dw6/DRw6 and some newly defined HLA-D/DR antigens is rather low.
Marijan Gerenčer, Marija Tomašković, Slobodan Pfeifer, Vesna Mezulić, Andrija Kaštelan   +4 more
openaire   +2 more sources

Primed LD Typing: Reagent Preparation and Definition of the HLA‐D‐Region Antigens

Scandinavian Journal of Immunology, 1977
Primed LD typing cells were prepared against single HLA haplotypes within families and used to type a random panel of 48 individuals. PLT cells could be grouped on the basis of highly correlated responses with the panel test cells; the 21 different PLT cells could be used to define 6 different PL antigens. One of these, PL 3, was split by the responses
F H, Bach, E K, Jarrett-Toh, C J, Benike, C Y, Shih, E A, Valentine, P M, Sondel, M L, Bach   +6 more
openaire   +3 more sources

Correlations between HLA‐D/DR associated Primed Lymphocyte Typing (PLT) defined DP‐antigens, HLA‐D and HLA‐DR antigens

Tissue Antigens, 1981
A panel of 79 individuals were typed for HLA‐D/DR associated Primed Lymphocyte Typing (PLT) defined “DP”‐antigens, HLA‐D and HLA‐DR antigens. Typing for DP‐antigens was carried out with local PLT‐cells. HLA‐D and‐DR typing was performed with all homozygous typing cells and all DR‐antisera included in the 8th International Histocompatibility Workshop ...
N, Morling, B K, Jakobsen, P, Platz, L P, Ryder, A, Svejgaard, M, Thomsen   +5 more
openaire   +2 more sources

HLA-D antigen expression and Langerhans' cell infiltrates in thyroid tumors

Endocrine Pathology, 1995
Papillary carcinomas (PCs) of thyroid are among the most common but least aggressive human malignancies. The factors explaining the indolence of these tumors are unknown but host-tumor immune interactions may play a role. This study was designed to determine if there is morphologic evidence of these.
Simon L., Raphael, Sylvia L., Asa
openaire   +2 more sources

Structure of HLA-D/DR-BON Antigen

1989
The D-DR BON antigen was individualized among the DR blank specificities in 1986. Cells of this specificity were characterized by serologic unreactivity with all the allo-antisera of the 9th Histocompatibility Workshop and as being DQw1-positive. Studies in the French family BON by mixed lymphocyte culture allowed us to isolate a homozygous typing cell
J. Tkaczuk, M. Thomsen, M. Calot, A. Cambon-Thomsen, E. Ohayon   +4 more
openaire   +1 more source

Antigenic Products of the HLA-D Region

1981
A multitude of different cell-membrane alloantigens, complement factors, and components that may have important functions in the regulation of the immune response are controlled by the HLA genetic complex of chromosome 6 (W.F. Bodmer et al., 1978). In this chapter, the identification, structure, tissue distribution, and clinical importance of the HLA-D-
B. G. Solheim, D. Albrechtsen, E. Thorsby   +2 more
openaire   +1 more source

HLA‐D/DR Restriction of Macrophage‐dependent Antigen Activation of Immune T Lymphocytes: Cross‐reacting Allogeneic HLA‐D/DR May Partly Substitute for Self HLA‐D/DR

Scandinavian Journal of Immunology, 1980
Optimal proliferative response of T lymphocytes to purified protein derivative of tuberculin (PPD) III vitro requires that antigen be presented by autologous macrophages or allogeneic macrophages sharing HLA‐D/DR determinants with the T cell donor. In some cases, however, T cells may respond to a limited extent to PPD in association with macrophages ...
B O, Bergholtz, A B, Thoresen, E, Thorsby   +2 more
openaire   +2 more sources

HLA‐D restriction of antigen‐specific proliferative T cell responses

Tissue Antigens, 1983
The specificity of the inhibitory activity of anti HLA‐DR antisera on the proliferative response of human T cells to soluble antigens has been recently challenged. Furthermore, there are conflicting reports about the effect of antisera to the stimulatory antigen.
E. Thorsby, S. Ferrone, H. Nousiainen, H. Hirschberg   +3 more
openaire   +1 more source