Results 241 to 250 of about 375,043 (313)
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Two‐Chain Subunit Structure of HLA‐D Antigens
Tissue Antigens, 1977Both F(ab′)2 fragments and intact antibody from rabbit anti‐B‐cell antisera were shown to specifically block the mixed lymphocyte culture (MLC) reaction. The antisera, which were raised to papain‐solubilized spleen cell membrane antigens, appeared to block the stimulator cell and not the responder cell.
R, Billing, M, Safani, J, Lesch
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Frequency of nine HLA—D antigens in the Danish population
Tissue Antigens, 1982The frequency of HLA—Dw1—8 and DH was determined in 389 unrelated healthy Danes and in 257 kidney patients. All individuals were HLA—A, B, C typed, 168 of the normal individuals and all kidney patients were typed for HLA‐DR.The frequency of Dw1—8 in the normal material and kidney patient material was quite similar except for Dw6, which showed an ...
M, Thomsen +5 more
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T cell clones restricted to "hybrid" HLA-D antigens?
The Journal of Immunology, 1982Abstract The genetics of T lymphocyte/accessory cell interactions were studied by using antigen-specific monoclonal T cell lines from human peripheral blood and X-irradiated non-T cells (E rosette-depleted) as accessory cells. The T cell lines were obtained by expanding single colonies from soft agar-cloned E rosette-positive lymphocytes,
G S, Hansen +2 more
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HLA-D--related (DRw) antigens in juvenile diabetes mellitus
Diabetes, 1979We studied the distribution of HLA-D–related (DRw) antigens in 40 patients with juvenile diabetes mellitus (JDM) and 79 matched controls. We found that DRw2 was significantly decreased in the JDM group, suggesting a protective effect of the antigen and that the decrease observed in B7 was secondary.
N R, Farid +5 more
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HLA antigens in Asian Indians: HLA-D-DR relationships
Human Immunology, 1981Fifty-nine Asian Indians were typed for HLA-A, B, D, and DR antigens. Peculiar to the population that we have tested was the absence of HLA-A25, B13, B14, DR1, DW1, LD13 (a DR1-associated HLA-D allele), and LD12 (a DR4-associated HLA-D allele). Certain haplotypes that exhibit high frequencies in Caucasians (such as A2-BW50, AW24-B18, B8-DR3, BW44-DR7 ...
N, Suciu-Foca +8 more
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Human Ia‐Like Antigens Associated with HLA‐D
Scandinavian Journal of Immunology, 1977Antisera raised within HLA‐A‐ and ‐B‐compatible, HLA‐D‐disparate combinations were cytotoxic to B lymphocytes from the immunizing donor and to B lymphocytes from most or all cell donors sharing the immunizing donor's HLA‐D phenotype. Four antisera recognized structures closely associated with the HLA‐D determinants Dw2, Dw3, Dw4, and LD 108.
D, Albrechtsen, B G, Solheim, E, Thorsby
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HLA‐D‐Associated Ia‐Like’ Antigens on Human Macrophages
Scandinavian Journal of Immunology, 1977Human macrophages procured by culture of adherent peripheral blood mononuclear cells were investigated for reactivity in complement‐dependent cytotoxicity tests with antisera having specificity for HLA‐D‐associated ‘Ia‐like’ B‐cell antigens. The antisera were found to be cytotoxic for 30%–70% of the macrophages from donors whose B cells were also ...
D. Albrechtsen
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HLA-D Antigens in Rheumatoid Arthritis and Toxicity to Gold and Penicillamine
Scandinavian Journal of Rheumatology, 1986The frequencies of HLA-D antigens were investigated in 77 Finnish patients who met the ARA criteria of classical or definite rheumatoid arthritis. The control material consisted of healthy blood donors. HLA-Dw4 was significantly (p less than 0.01) increased and HLA-Dw2 significantly (p less than 0.01) decreased in the patients.
P, Nuotio, M, Nissilä, J, Ilonen
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HLA-D related (DR) antigens in various kinds of myositis
Human Immunology, 1981Forty-eight patients with various kinds of myositis were studied for HLA-A, B, C, and DR antigens and compared to both local and 7th International Workshop controls. No A, B, or C antigens were increased except for B8 in white patients (7/13 or 54%) (p = 0.005, pc = NS) and for B7 in black patients (6/9 or 67%) (p = 0.02, pc = NS).
T J, Hirsch +3 more
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Dissimilar Effects of Ultraviolet Light on HLA‐D and HLA‐DR Antigens
Tissue Antigens, 1980Since HLA‐DR antigens are closely related to HLA‐D antigens, we studied the effect of low‐dose ultraviolet irradiation on the ability of human lymphocytes to induce a proliferative response in mixed lymphocyte culture (HLA‐D) and on the serologic reactivity of B lymphocyte HLA‐DR antigens.
L M, Slater +3 more
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