Results 171 to 180 of about 188,808 (295)

Cytotoxic Lymphocyte Recognition of HLA-E [PDF]

Immunity, 1998
openaire   +1 more source

Unconventional CD8⁺ T cell surveillance of cytomegalovirus via Qa-1/HLA-E-restricted epitope recognition. [PDF]

Sci Adv
Reilly SP, Smith ML, Borys SM, Fugère C, Demers D, Hogan MJ, Zemmour D, Brossay L.   +7 more
europepmc   +1 more source

Shared HLA-E and Mamu-E Peptide Repertoires With Subtle Peptide Binding Differences Revealed by Combined nDSF- and Fluorescence Polarisation-Based Methods. [PDF]

Eur J Immunol
Quastel MN, Ranawana SA, Peeters BWA, van Hateren A, McMichael AJ, Gillespie GM.   +5 more
europepmc   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Full-length gene polymorphism of the non-classical HLA-E in Estonian individuals. [PDF]

Immunogenetics
Olieslagers TI, Tagen I, Groeneweg M, Tilanus MGJ, Wieten L, Voorter CEM.   +5 more
europepmc   +1 more source

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

CD8+ T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles. [PDF]

JCI Insight
Maroney KJ, Rose MA, Oman AK, Chopra A, Hsieh HS, Derza Z, Waterworth R, Brockman MA, Kalams SA, Bansal A, Goepfert PA.   +10 more
europepmc   +1 more source

Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis. [PDF]

Sci Immunol, 2023
Jost S, Lucar O, Lee E, Yoder T, Kroll K, Sugawara S, Smith S, Jones R, Tweet G, Werner A, Tomezsko PJ, Dugan HL, Ghofrani J, Rascle P, Altfeld M, Müller-Trutwin M, Goepfert P, Reeves RK.   +17 more
europepmc   +1 more source

Multimodal Integration of Protein Interactomes With Genomic and Molecular Data Discovers Distinct Rheumatoid Arthritis Endotypes

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease characterized by clinical and molecular heterogeneity, notably in the presence of anti–cyclic citrullinated peptide (CCP) antibodies. Patients with CCP+ RA exhibit more severe disease progression and distinct treatment responses compared to patients with CCP− RA.
Javad Rahimikollu, Priyamvada Guha Roy, Akash Kishore, Danica Morgan Lee, Lauren A. Vanderlinden, Kiran Nazarali, Fan Zhang, Dana P. Ascherman, Daniella M. Schwartz, Larry Moreland, Jishnu Das   +10 more
wiley   +1 more source

IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis. [PDF]

J Ovarian Res, 2023
Zheng H, Guan X, Meng X, Tong Y, Wang Y, Xie S, Guo L, Lu R.   +7 more
europepmc   +1 more source