Results 1 to 10 of about 121,761 (316)
MR1- and HLA-E-Dependent Antigen Presentation of Mycobacterium tuberculosis
International Journal of Molecular Sciences, 2022 MR1 and HLA-E are highly conserved nonclassical antigen-presenting molecules. They can present antigens derived from Mycobacterium tuberculosis to a distinct subset of MR1-restricted or HLA-restricted CD8+ T cells. MR1 presents small microbial metabolites, and HLA-E presents peptides and glycopeptides.
Se-Jin Kim, Elham Karamooz
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Current research status of HLA in immune‐related diseases
Immunity, Inflammation and Disease, 2021 Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
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The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. [PDF]
PLoS Pathogens, 2009 Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-gamma
Jeff E Grotzke +6 more
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Bioengineering, 2023 Background: Limited graft availability is a constant clinical concern. Hence, the umbilical cord (UC) is an attractive alternative to autologous grafts.
Yue Ying Yao +7 more
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HLA-E–dependent Presentation of Mtb-derived Antigen to Human CD8+ T Cells [PDF]
The Journal of Experimental Medicine, 2002 Previous studies in mice and humans have suggested an important role for CD8+ T cells in host defense to Mtb. Recently, we have described human, Mtb-specific CD8+ cells that are neither HLA-A, B, or C nor group 1 CD1 restricted, and have found that these cells comprise the dominant CD8+ T cell response in latently infected individuals.
Heinzel, Amy S. +9 more
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PECULIARITIES OF HLA-PHENOTYPES IN PATIENTS WITH PYELONEPHRITIS [PDF]
Annals of Mechnikov's Institute, 2016 Introduction. Of great interest are the studies on the role of human leucocyte antigens (HLA) in pathogenesis of a disease. The kidneys is vulnerable to injury in the context of inflammatory responses, with the potential involvement of a number of ...
Haiseniuk F, Driyanska V, Kruglikov V
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Hematology, Transfusion and Cell Therapy, 2023 Introdução: A lesão pulmonar aguda relacionada à transfusão (TRALI), reação que pode ocorrer dentro de 6 horas, é uma condição rara e que há indícios do envolvimento de anticorpos anti-antígeno leucocitário humano (HLA) e anti-antígeno neutrofílico ...
LFM Fontes +3 more
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Non-classical human leucocyte antigens in ankylosing spondylitis: possible association with HLA-E and HLA-F [PDF]
RMD Open, 2018 Objectives Ankylosing spondylitis (AS) is the most prevalent form of spondyloarthritis, with a known genetic association with the HLA-B27 molecule. The aim of this study was to assess the contribution of the HLA-G, HLA-E and HLA-F to AS susceptibility/protection in Portuguese patients with HLA-B27 AS and HLA-B27 ...
Santos, Margarida +14 more
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ANTíGENOS HLA ESTÃO ASSOCIADOS A RISCO DE DIABETES MELLITUS PÓS-TRANSPLANTE?
Brazilian Journal of Transplantation, 2021 Introdução: Diabetes mellitus pós-transplante (DMPT) tem impacto na morbidade e na mortalidade em receptores de transplante renal, uma vez que aumenta o risco de complicações cardiovasculares e de perda do enxerto renal.
Débora Dias de Lucena +5 more
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HLA Typing in Turkish Patients with Paget's Disease of Bone
Endocrinology Research and Practice, 2022 Paget's disease of bone is a disorder of bone, primarily affecting elderly population. The disease causes a structural disorganisation of of bone tissue in affected sites. The etiology is unknown.
Gürcan Kısakol +3 more
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