Results 61 to 70 of about 31,480,937 (161)

Single Nucleotide and Copy-Number Variants in IL4 and IL13 Are Not Associated with Asthma Susceptibility or Inflammatory Markers: A Case-Control Study in a Mexican-Mestizo Population

Diagnostics, 2020
Background: Asthma is a complex and chronic inflammatory airway disease. Asthma’s etiology is unknown; however, genetic and environmental factors could affect disease susceptibility.
Enrique Ambrocio-Ortiz, Gustavo Galicia-Negrete, Gloria Pérez-Rubio, Areli J. Escobar-Morales, Edgar Abarca-Rojano, Alma D. Del Angel-Pablo, Manuel D. J. Castillejos-López, Ramcés Falfán-Valencia   +7 more
doaj   +1 more source

Completion of HLA protein sequences by automated homology-based nearest-neighbor extrapolation of HLA database sequences [PDF]

, 2016
The IMGT/HLA database contains every publicly available HLA sequence. However, most of these HLA protein sequences are restricted to the alpha-1/alpha-2 domain for HLA class-I and alpha-1/beta-1 domain for HLA class-II.
Geneugelijk, K, de Hoop, T, Spierings, E, Niemann, M   +3 more
core   +1 more source

Human leukocyte antigen-E mismatch is associated with better hematopoietic stem cell transplantation outcome in acute leukemia patients

Haematologica, 2017
The immunomodulatory role of human leukocyte antigen (HLA)-E in hematopoietic stem cell transplantation (HSCT) has not been extensively investigated.
Chrysanthi Tsamadou, Daniel Fürst, Vladan Vucinic, Donald Bunjes, Christine Neuchel, Daphne Mytilineos, Martin Gramatzki, Renate Arnold, Eva Maria Wagner, Hermann Einsele, Carlheinz Müller, Hubert Schrezenmeier, Joannis Mytilineos   +12 more
doaj   +1 more source

Freqüência dos antígenos HLA- A e HLA- B em populações das regiões de Curitiba e Norte/Noroeste do Estado do Paraná

Acta Scientiarum. Health Sciences, 2008
Os antígenos HLA- A e B são glicoproteínas de superfície celular, expressos em todas as células nucleadas e responsáveis pela apresentação dos antígenos aos linfócitos T durante o desenvolvimento da resposta imune.
Marcia Machado de Oliveira Dalalio, Ana Maria Sell, Lia Yoneka Toda, Marcelo Fabricio F. Cano, Cintia Regina Sossai, Lawrence Fracalossi   +5 more
doaj   +1 more source

HLA and hemochromatosis disease association in São Miguel Island [PDF]

, 2008
Mestrado em Biologia Molecular e CelularA hemocromatose hereditária uma doença autossómica recessiva do metabolismo do ferro, geralmente associada à mutação C282Y no gene HFE. Presume-se que a origem desta mutação tenha ocorrido por acaso no haplótipo
Gomes, Cidália Maria Teixeira
core  

Presence of an expressed 13-tubulin gene (TUBB) in the HLA class I region may provide the genetic basis for HLA-linked microtubule dysfunction [PDF]

, 1994
An expressed beta-tubulin gene (TUBB) has previously been localized to chromosome region 6pter-p21 in man. By using a panel of deletion mutant cell lines and radiation-reduced hybrids containing fragments of chromosome 6, the TUBB locus could be mapped ...
Trowsdale, John, Volz, Armin, Ziegler, Andreas, Weiss, Elisabeth H.   +3 more
core   +1 more source

HLA-E/Mtb specific CD4+ and CD8+ T cells have a memory phenotype in individuals with TB infection

Frontiers in Immunology
IntroductionTuberculosis (TB) is the deadliest infectious disease worldwide and novel vaccines are urgently needed. HLA-E is a virtually monomorphic antigen presentation molecule and is not downregulated upon HIV co-infection.
Linda Voogd, Catherine Riou, Catherine Riou, Thomas J. Scriba, Marjolein van Wolfswinkel, Krista E. van Meijgaarden, Kees L. M. C. Franken, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Tom H. M. Ottenhoff, Simone A. Joosten   +12 more
doaj   +1 more source

Role of HLA-B Leader Peptides and HLA-E Genetic Variants in HIV Infection

Experimed
Objective: This study assessed whether human leukocyte antigen (HLA)-B signal peptide dimorphism at position −21 (HLA-B-21) Methionine/Threonine (M/T) and HLA-E polymorphisms are associated with the level of viremia in human immunodeficiency virus (HIV ...
Yeliz Öğret, Çiğdem Kekik Çınar, Arif Atahan Çağatay, Hayriye Şentürk Çiftçi, Kürşat Özdilli, Fatma Savran Oğuz   +5 more
doaj   +1 more source

HLA-A*02 allele and HLA-E genotype influence the development of HLA-E_UL40-specific CD8 T cells in HCMV⁺ individuals.

, 2018
(A) HLA-A*02 allele frequency and (B) genotype distribution were investigated in HCMV- (n = 39) versus HCMV+ (n = 105) individuals including a total of 144 healthy volunteers and kidney transplant recipients (left panels) and in HCMV+ host with (+, n ...
Céline Bressollette-Bodin (5155148), Nicolas Jouand (5155151), Nathalie Gérard (2632051), Mathilde Allard (114723), Magali Giral (221237), Audrey Rodallec (4261540), Romain Oger (114727), Anne Cesbron-Gautier (5155145), Nadine Gervois (114738), Béatrice Charreau (114735), Pierrick Guérif (5155142), Tiphaine Parrot (5155154)   +11 more
core   +1 more source

Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk [PDF]

, 2012
Objective: The identification of a vitamin D-responsive (VDRE) motif within the HLA-DRB1*15:01 promoter region provides an attractive explanation for the combined effects of HLA-DR inheritance and vitamin D exposure on multiple sclerosis (MS) risk.
Qiu, W., Nolan, D., Kermode, A., Tschochner, M., Mastaglia, F., Christiansen, F.T., Witt, C., Castley, A., James, I., Sayer, D., Carroll, W.   +10 more
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